MétaCan
Menu
Back to cohort
Record W4307414372 · doi:10.21203/rs.3.rs-2195140/v1

Antibacterial and cytotoxic efficacy of Nano- Hydroxyapatite Synthesized from Eggshell and Sheep bones bio Waste

2022· preprint· en· W4307414372 on OpenAlexaff
Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, khadijeh Yousefi, N. Vijayakameswara Rao, Navid Omidifar, Ahmad Gholami, Yasamin Ghahramani, Wei‐Hung Chiang, Fatemeh Fallahi Nezhad, Masoomeh Yari Kalashgrani

Bibliographic record

VenueResearch Square · 2022
Typepreprint
Languageen
FieldEngineering
TopicBone Tissue Engineering Materials
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsEnterococcus faecalisAntibacterial activityCalcinationBacteriaEggshellMaterials scienceBiocompatibilityChemistryMicrobiologyFood scienceNuclear chemistryStaphylococcus aureusBiologyOrganic chemistryMetallurgy

Abstract

fetched live from OpenAlex

Abstract Background:Through a new material pattern addition approach, NHA is synthesized using eggshell materials and sheep bone under different calcination temperatures (respectively at 900 ° C and 800 ° C) using a sol-gel approach. NHA/Es and NHA/Sb, due to their biocompatibility and bioactivity, are widely used in applications such as antibacterial and cytotoxic of PDL cells and teeth and as hard tissue. Results: We investigated the physicochemical properties of NHA/Es and NHA/Sb by performing FTIR, energy scattering X-ray analysis, SEM, and XRD. The formation of NHA / Es, NHA / Sb particles occurs due to the usage of Eggshell materials and sheep bones as a pattern in NHA synthesis, which are less crystalline. Results of surface morphology analysis of NHA particles indicate that these particles are discrete and rod-shaped at low temperatures (850 °C), whereas larger particles are formed at higher temperatures. Therefore, antibacterial activity against four gram-negative bacteria were investigated through MIC and MBC methods, which included E. coli, Pseudomonas aeruginosa, Candida, Saccharomyces and gram-positive bacteria including Staphylococcus aureus and Enterococcus faecalis. Conclusions:The reason for the compatibility of calcined NHA / Sb powder as a substance used in biomedical applications is that this powder has shown strong antibacterial efficacy against all bacterial strains with a range of inhibitory zones. The nature and structure of PDLs have been studied in many studies; While we focus on the quantitative analysis of the structural properties of PDL cells and their cytotoxic activity through the use of bio waste materials.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.002

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.296
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2022
Admission routes1
Has abstractyes

Explore more

Same venueResearch SquareSame topicBone Tissue Engineering MaterialsFrench-language works237,207