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Record W4307414412 · doi:10.21203/rs.3.rs-2187235/v1

Frequency-specific brain network architecture in resting-state fMRI

2022· preprint· en· W4307414412 on OpenAlexaff
Shogo Kajimura, Daniel S. Margulies, Jonathan Smallwood

Bibliographic record

VenueResearch Square · 2022
Typepreprint
Languageen
FieldNeuroscience
TopicFunctional Brain Connectivity Studies
Canadian institutionsQueen's University
Fundersnot available
KeywordsResting state fMRIFunctional magnetic resonance imagingDefault mode networkCluster analysisComputer scienceFrequency bandRadio spectrumFrequency analysisPattern recognition (psychology)Network architectureBrain functionFunctional connectivityBrain mappingNeuroscienceArtificial intelligencePsychologyAlgorithmTelecommunicationsComputer network

Abstract

fetched live from OpenAlex

Abstract The analysis of brain function in resting-state network (RSN) models, which has been found in the functional connectivity pattern of resting-state functional magnetic resonance imaging (rs-fMRI), is sufficiently powerful for studying large-scale functional integration of the brain. Although there has been an increasing interest in the relatively higher frequency of rs-fMRI data, the network architecture has been regarded as the same through different frequency bands in RSN-based research. This study examined whether the network architecture changes with frequency. The blood-oxygen-level-dependent (BOLD) signal was decomposed into four frequency bands (ranging from 0.007 Hz to 0.438 Hz), for each of which the clustering algorithm was applied. The best clustering number was selected for each frequency-band based on the overlap ratio with task activation maps provided by Neurosynth. The results demonstrate that (1) resting-state BOLD signals have frequency-specific network architecture, that is, the networks finely subdivided in the lower frequency bands are integrated into fewer networks in higher frequency bands rather than reconfigured, and (2) the default mode network(DMN) is the only associative network that has a strong enough architecture to survive the increasing noise in higher frequency bands. These findings provide a novel framework that enables a better understanding of brain function through the multiband frequency analysis of ultra-slow rs-fMRI data.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.114
GPT teacher head0.376
Teacher spread0.262 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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