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Record W4307885557 · doi:10.1186/s13024-022-00571-7

Common features of neurodegenerative disease: exploring the brain-eye connection and beyond (part 2): the 2021 pre-symposium of the 15th international conference on Alzheimer’s and Parkinson’s diseases

2022· article· en· W4307885557 on OpenAlexaff
Sharyn L. Rossi, Preeti Subramanian, Guojun Bu, Adriana Di Polo, Todd E. Golde, Diane E. Bovenkamp

Bibliographic record

VenueMolecular Neurodegeneration · 2022
Typearticle
Languageen
FieldNeuroscience
TopicNeurological Disorders and Treatments
Canadian institutionsCentre Hospitalier de l’Université de Montréal
FundersEmory UniversityBrightFocus Foundation
KeywordsNeuroscienceParkinson's diseaseNeurologyDiseaseMedicineConnection (principal bundle)Cognitive sciencePsychologyPathologyEngineering

Abstract

fetched live from OpenAlex

BrightFocus Foundation sponsored the third iteration of the "Common Features of Neurodegenerative Disease: Exploring the Brain-Eye Connection and Beyond" preconference symposium that preceded the 15th International Conference on Alzheimer's and Parkinson's Diseases (AD/PD 2021).Part 1 of the meeting report was previously published in Molecular Neurodegeneration.This completes the description of the meeting with Part 2. Session III, "Why are the vascular components and blood-brain/blood-retina barriers of the brain and eye important contributors to the tipping point between health and disease?" was chaired by Dr. Adriana Di Polo.Both the brain and the eye are highly vascularized organs that contain a dense capillary network.The neurovascular unit (NVU) is a community of cells including neurons, astrocytes, endothelial cells, pericytes, and

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.165
Threshold uncertainty score0.490

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.040
GPT teacher head0.265
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2022
Admission routes1
Has abstractyes

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