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Record W4308454291 · doi:10.18280/ijdne.170515

The Contribution of Interleukin (17) in Iraqi Patients with Type I Diabetic and Positive Agglutination Sera with Morganella Morganii Antigens

2022· article· en· W4308454291 on OpenAlexvenueno aff
Fatima Rammadan Abdul, Maysoon Kh. Abbas, Khetam Habeeb Rasool, Ihsan Ali Raheem

Bibliographic record

VenueInternational Journal of Design & Nature and Ecodynamics · 2022
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicDiabetes and associated disorders
Canadian institutionsnot available
FundersMustansiriyah University
KeywordsMorganella morganiiTiterDirect agglutination testAntigenDiabetes mellitusMedicineAntibodyUrinePopulationImmunologyInternal medicineGastroenterologyMicrobiologyBiologySerologyEndocrinologyEnterobacteriaceaeEscherichia coli

Abstract

fetched live from OpenAlex

Background: The rising population of patients with diabetes type 1 has caused in a fast increase in the amount of patients who have diabetic complications. Objective: Isolation of bacteria from diabetic patients and detection of their antibodies in the serum of patients and rabbits. Materials and Methods: Sixty samples of blood and urine were collected from diabetic patients, a similar proportion of genders were included in 50 samples of blood from healthy as controls. Patients with diabetes diseases diagnosed by a physician collected from specialized center for endocrinology and diabetes and Kindy hospital, in Baghdad. Results: This study showed that Morganella morganii (n=9, 18%) was isolated from urine of patients. With M. morganii antigens (complete cells) as three bacteria antigens agglutinated in titer 1:64 and three in titer 1:128 of serum of patients (antibodies) whereas 1 and fife of M. morganii antigens agglutinated in serum of patients in titer 1:256 and 1:16 Consecutively. Determination of the concentration of cytokinetic proteins IL-17, using an ELISA device. The concentration of some inflammation-initiating cytokines was estimated in the serum of the studied samples, which included using IL-17 ELISA technology. The statistical results by t-test showed were significant differences between this interleukin between the patients and the control sample and under the probability level P<0.05 in the serum of the patients compared to the control sample. The results also showed a decrease in the cytokinetic concentration, as the concentration in the infected serum was 0.011 ± 0.019 (pg/mm), while its concentration in the control sample was 0.007 ± 0.033 (pg/mm) in the infected serum. Recognize the agglutination ability slide agglutination exam (anti Morganella morganii rabbit serum). Conclusion: The ability of killed antigen bacteria isolated from diabetic patients to agglutinate with their serum, and its ability to agglutinate with the serum of rabbits injected with this bacterium. The increased prevalence of agglutination and increased antibodies of patients and rabbit blood suggest this as part of the multifactorial basis for disease penetrance and susceptibility.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.002
GPT teacher head0.193
Teacher spread0.192 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2022
Admission routes1
Has abstractyes

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