Experience of work as an extemporal pharmacy and providing the population with medicines under the conditions of the martial law
Bibliographic record
Abstract
Aim. To highlight the expediency of reviving extemporaneous formulations as a necessary condition for fully providing the population of Ukraine with individualized medicinal products that can be also used in conditions of the martial law and emergency situations. Materials and methods. Publications and our own research of the activities of pharmacy No. 80 in Slovyansk, Donetsk region, with extemporaneous compounding of medicines were used. The following methods were used in the work: system analysis, synthesis, own observations and generalization of data. Results and discussion. From a professional point of view, medicinal products extemporaneously manufactured are a unique attribute of pharmacy practice, which reflects the professional status of pharmacists, particularly hospital pharmacists. Despite a significant reduction in the range and quantity of pharmacy-made medicines in pharmacies, they continue to retain important functions (medical, therapeutic, social). During the period from February 24, 2022 to March 9, 2022, sale volumes of the most popular medicines increased significantly. Suspensions for external use were in the greatest demand, in particular, the universal white lotion doubled in dispensing (from 4 to 8 bottles per day), as well as sedative drugs (Quarter’s mixture) – more than five times (from 2 to 13 bottles day). The number of powders (with different dosages of captopril, verospiron, furosemide, anaprilin, euthyrox, etc.) for children in one order could befrom 30-50 doses to 90-120 doses, and one child sometimes had 2-3 names of prescribed medicines, i.e. the number of doses of the daily compounding of powders reached 200-300 pieces for one consumer. Conclusions. Today, an important task of domestic pharmacy is not only to preserve extemporaneous formulations, but also to improve them and develop new magistral formulas using professional recommendations and professional advice.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.004 | 0.005 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.006 | 0.005 |
| Scholarly communication | 0.005 | 0.003 |
| Open science | 0.001 | 0.007 |
| Research integrity | 0.001 | 0.003 |
| Insufficient payload (model declined to judge) | 0.009 | 0.002 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".