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Record W4309736518 · doi:10.34883/pi.2022.13.3.003

Clinical Characteristics of Schizophrenic Patients with Postpsychotic Depression in Context of Mental Pain Phenomenon

2022· article· ru· W4309736518 on OpenAlexaboutno aff
В.В. Савицкая, О.А. Скугаревский, В.Г. Объедков

Bibliographic record

VenueПсихиатрия психотерапия и клиническая психология · 2022
Typearticle
Languageru
FieldPsychology
TopicMental Health Treatment and Access
Canadian institutionsnot available
Fundersnot available
KeywordsPositive and Negative Syndrome ScaleSchizophrenia (object-oriented programming)Depression (economics)Context (archaeology)PsychologyPsychiatryInternal medicineClinical psychologyExtrapyramidal symptomsMedicinePsychosisAntipsychotic

Abstract

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В данной статье представлены результаты изучения клинических характеристик 152 пациентов с шизофренией с постпсихотической депрессией в контексте феномена душевной боли. Дизайн исследования: открытое обсервационное поперечное исследование с направленным формированием групп сравнения. Инструменты исследования: диагностика клинических симптомов шизофрении проводилась с применением шкалы PANSS, для детализации депрессии была использована шкала депрессии при шизофрении Калгари. Критериями включения пациентов в общую исследовательскую выборку являлись: верифицированный диагноз «шизофрения» (по МКБ-10), возраст 18–50 лет, отсутствие у пациента выраженных острых психотических симптомов (по шкале PANSS сумма позитивных симптомов <30 баллов), отсутствие выраженных негативных симптомов (по шкале PANSS сумма негативных симптомов <35 баллов), письменное информированное согласие на участие в исследовании. Критерием исключения пациентов из общей выборки являлось наличие экстрапирамидных расстройств. Пациенты были разделены в два этапа на три исследуемые группы: группу А – 103 пациента (постпсихотическая депрессия, значения по шкале депрессии PANSS ≥5 баллов), группу Б – 49 пациентов (отсутствие постпсихотической депрессии, значения по шкале депрессии PANSS <5 баллов); на втором этапе группа А была разделена на две подгруппы – А1, 69 пациентов (постпсихотическая депрессия с душевной болью), и А2 – 34 пациента (постпсихотическая депрессия без душевной боли). Критической точкой для разделения на подгруппы явилось значение ≥24 балла по шкале душевной боли. По результатам исследования были сделаны следующие выводы: пациенты с шизофренией с депрессией и душевной болью образуют особую группу с клиническими особенностями в каждом психопатологическом домене – позитивном, негативном и общем по шкале PANSS. Для них характерны слабая выраженность апатии, концептуальной дезорганизации, нарушений абстрактного мышления, нарушений мышления в форме стереотипий, а также высокие уровни тревоги, соматической озабоченности и напряженности. This article presents the results of studying the socio-demographic and clinical-dynamic characteristics of 152 schizophrenic patients with postpsychotic depression in context of mental pain phenomenon. Study design: open, observational, cross-sectional study with directional formation of comparison groups. Research instruments: clinical symptoms of schizophrenia were diagnosed using the PANSS scale, and the Calgary Depression Scale for Schizophrenia was used to detail depression. The criteria for patients inclusion in the general research sample were: verified diagnosis of schizophrenia (according to ICD-10); age of 18–50 years; absence of significant acute psychotic symptoms (according to the PANSS scale, the sum of positive symptoms <30 points), absence of significant negative symptoms (on the PANSS scale, the sum of negative symptoms <35 points), written informed consent for participation in the study. The criteria for patients exclusion from the general sample were: presence of significant acute psychotic symptoms (according to the PANSS scale, the sum of positive symptoms >30 points), significant manifestations of personality defect (according to the PANSS scale, the sum of negative symptoms >35 points), and the presence of extrapyramidal disorders. Patients were divided in two stages into three study groups: group A, 103 patients (postpsychotic depression, PANSS depression scores ≥5 points) and group B, 49 patients (no postpsychotic depression, PANSS depression scores <5 points). At the second stage, group A was divided into two subgroups: A1, 69 patients (postpsychotic depression with mental pain) and A2, 34 patients (postpsychotic depression without mental pain). The critical point for subgrouping was ≥24 points on the mental pain scale. According to the results of the study, the following conclusions were drawn: schizophrenic patients with depression and mental pain form a special group with distinct clinical features in each psychopathological domain: positive, negative, and overall on the PANSS scale. They are characterized by a weak severity of violations of the mental sphere: weakly expressed apathy, conceptual disorganization, abstract thinking disorders and thinking disorders in the form of stereotypes, as well as high levels of anxiety, somatic concern and tension.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.351
Teacher spread0.325 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2022
Admission routes1
Has abstractyes

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