Unexplained Stroke and Multifocal Intracranial Stenosis due to Varicella Zoster Virus Vasculopathy
Bibliographic record
Abstract
The classical prototype of Varicella Zoster Virus (VZV) associated vasculopathy is contralateral hemiplegia after herpes zoster ophthalmicus. We describe a 30-year-old patient with no vascular risk factors who presented with a lacunar stroke and was found to have focal intracranial stenosis. He presented again one and a half months later with new findings suggestive of progressive multifocal intracranial stenoses. Although vasculitis was suspected initially, varicella zoster virus reactivity raised the possibility of VZV associated vasculopathy. This case serves as a reminder to suspect this type of vasculopathy even in immunocompetent patients with no cutaneous manifestations. Intracranial stenosis affecting M1 of the middle cerebral artery and the distal portion of the internal carotid artery is common in VZV vasculopathy and should hint toward the diagnosis as shown in this case.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.002 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".