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Record W4311564993 · doi:10.21203/rs.3.rs-2267501/v1

A Comprehensive Health Effects Assessment of the Use of Sanitizers and Disinfectants during COVID-19 Pandemic: A Global Survey

2022· preprint· en· W4311564993 on OpenAlex
Fallah Hashemi, Lori Hoepner, Farahnaz Soleimani Hamidinejad, Daniela Haluza, Sima Afrashteh, Alireza Abbasi, Elma Omeragić, Belma Imamović, Narin A. Rasheed, Taqi Mohammed Jwad Taher, Fitri Kurniasari, Dhuha Youssef Wazqar, Özge Ceren Apalı, Ayça DEMİR YILDIRIM, Bo ‍Zhao, Zaruhi Kalikyan, Cui Guo, Andrea Chong Valbuena, Magdalena Mititelu, Carolina Martínez Pando, Maria Saridi, Aikaterini Toska, Magalys López Cuba, Precious Kwablah Kwadzokpui, Niguse Tadele Atnafu, Tohfa Nasibova, Stefanie Harsch, Luvsan Munkh-Erdene, Wafaa Menawi, Efi Evangelou, Antoniya Dimova, Dimitar Marinov, Tеодора Димитрова, Anna Shalimova, Howieda Fouly, Anna Suraya, Juliana Pereira da Silva Faquim, Bouadil Oumayma, Maria Antonieta Annunziato, Rezarta Lalo, Evridiki Papastavrou, Anju Damu Ade, Susanna Caminada, Svetlana Stojkov, Carmen Gloria Narváez, Lutendo Sylvia Mudau, Ines Rassas, Daphnée Michel, Nur Sema Kaynar, Sehar Iqbal, Halla Elshwekh, Irin Hossain, Sadeq AL‐Fayyadh, A. S. Sydorchuk, Dua’a Mohammad Hasan Alnusairat, Asli Mohamed Abdullahi, Neelam Iqbal, Apsara Pandey, Brenda Gómez-Gómez, Ayşenur Günaydın Akyıldız, Elena Moroșan, Daniella Dwarica, Gantuya Dorj, Sumaya Yusuf Hasan, Noha M. Alshdefat, Bojana Knežević, Wendy Valladares, Cecilia Severi, María Sofía Cuba-Fuentes, Sofia Augusto, Elizaveta Sidorova, Anita Dewi Moelyaningrum, Tafaul Alawad, Atiqa Khalid, Elehamer Nafisa Mhna Kmbo, Anna Mihaylova, Оxana Tsigengagel, Aziza Menouni, Agnieszka Wojtecka, Rozita Hod, Yusuf Banke Idayat, khadija Othman, Rim Harfouch, Tsonco Paunov, Meruyert Omar, Nana Christine Benderli, Globila Nurika, Sana Amjad, Salma Elnoamany, fatma El-esrigy, Marwa Mamdouh Shaban, Doménica Acevedo-López, Maria Kartashova, Atika Khalaf, Sabah Abdullah Jaafar, Taisir Abdulelah Kadhim, Nada Hweissa, Yulong Teng, Fatima Elbasri Abuelgasim Mohammed, Thayahlini Sasikumar, Christabel Nang’andu Hikaambo, Aditi Kharat, ulyana Lyamtseva, Maya Aldeeb, Natalia Pawlas, Lkhagvasuren Khorolsuren, Roopeshwaree Pallavi Koonjul, Halima Boubacar Maïnassara, Priyanka Chahal, Rose W. Wangeci, Ainur B. Kumar, Irina Zamora‐Corrales, Stella Gracy, Maimouna Mahamat, Jakub Adamczyk, Haliza Abdul Rahman, Lolita Matiashova, Omneya Ezzat Elsherif, Nazdar Ezzaddin Alkhateeb, Yamilé Aleaga, Shima Bahrami, Shaimaa Rahem Al-salihy, Paula Cabrera‐Galeana, Mladena Lalić‐Popović, Eugenie Brown-Myrie, Divya Bhandari, Cinderella Akbar Mayaboti, Svetlana Stanišić, Sanda Kreitmayer Peštić, Muhammed Yunus Bektay, Haleama Al Sabbah, Saber Hashemi, Assia Bouchetara, Anne‐Sophie Merritt, Zhian Ramzi, Himawatee Baboolal, Juman Isstaif, Rula Shami, Rahma Saad, Temwanani Nyirongo, Mohammad Hoseini

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueResearch Square · 2022
Typepreprint
Languageen
FieldMedicine
TopicHealthcare and Environmental Waste Management
Canadian institutionsInstitute on GovernanceUniversity of AlbertaHealth Sciences North
FundersShiraz UniversityShiraz University of Medical Sciences
KeywordsCoronavirus disease 2019 (COVID-19)Pandemic2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Hand sanitizerEnvironmental healthBusinessChemistryVirologyMedicineFood scienceOutbreakInfectious disease (medical specialty)

Abstract

fetched live from OpenAlex

Abstract COVID-19 has affected all aspects of human life so far. From the outset of the pandemic, preventing the spread of COVID-19 through the observance of health protocols, especially the use of sanitizers and disinfectants was given more attention. Despite the effectiveness of disinfection chemicals in controlling and preventing COVID-19, there are critical concerns about their adverse effects on human health. This study aims to assess the health effects of sanitizers and disinfectants on a global scale. A total of 91056 participants from 154 countries participated in this cross-sectional study through an electronic questionnaire. Results implied that detergents (67%), alcohol-based materials (56%), and chlorinated compounds (32%) were the most commonly used types of sanitizers and disinfectants. Most frequently reported health issues include skin complications 48.8% and respiratory complications 29.8%. The Chi-square test showed a significant association between chlorinated compounds with all possible health complications under investigation (p-value < 0.001). Examination of risk factors based on multivariate regression analysis showed that alcohols-based materials were associated with skin complications (OR, 1.98; 95%CI, 1.87–2.09), per-chlorine was associated with eye complications (OR, 1.83; 95%CI, 1.74–1.93), and highly likely with itching and throat irritation (OR, 2.00; 95%CI, 1.90–2.11). Furthermore, formaldehyde was associated with a higher prevalence of neurological complications (OR, 2.17; 95%CI, 1.92–2.44). The findings of the current study suggest that health authorities need to implement more awareness programs about the side effects of using sanitizers and disinfectants during viral epidemics.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.029
Threshold uncertainty score0.983

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.004
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.335
GPT teacher head0.520
Teacher spread0.185 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it