Bullous pemphigoid treated with Janus kinase inhibitor upadacitinib
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Bullous pemphigoid (BP) is a chronic autoimmune blistering disorder defined by autoantibody formation to hemidesmosomal proteins in the basement membrane zone of the skin. This disease presents most commonly in elderly individuals as tense bullae on erythematous or normal skin, often affecting the trunk and extremities and accompanied by significant pruritus.1 Prompt therapeutic intervention allows for healing of eroded lesions and a reduction in morbidity/mortality (eg, secondary infections).1 Depending on the amount of cutaneous involvement, topical or systemic corticosteroids are traditionally used as the first-line treatment, and systemic immunosuppressive drugs, such as methotrexate or mycophenolate mofetil, are deployed as second-line agents in those with extensive or persistent disease.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it