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Record W4312444373 · doi:10.15406/ogij.2022.13.00660

The impact of endometriosis on embryo implantation in IVF procedures

2022· article· en· W4312444373 on OpenAlexaff
Murid Javed, Noura K Alfhead, Khaleel Al Yahya, Sameera Shaheen

Bibliographic record

VenueObstetrics & Gynecology International Journal · 2022
Typearticle
Languageen
FieldMedicine
TopicEndometriosis Research and Treatment
Canadian institutionsCReATe Fertility Centre
Fundersnot available
KeywordsEndometriosisMedicineInfertilityGynecologyObstetricsPregnancyStatistical significancePregnancy ratePelvic inflammatory diseasePelvic painEmbryo transferInternal medicineSurgeryBiology

Abstract

fetched live from OpenAlex

Embryo implantation is the most important event in the achievement of conception. In the presence of any endometrial disease, this process can be hampered. The endometriosis is linked to causing infertility. It is a chronic uterine disease that is dependent on estrogens and is associated with reduced fecundity. The objective of this study was to investigate the impact of endometriosis on embryo implantation in patients undergoing IVF. This is a case-control study, with case to control ratio of 5:1. The study included 50 patients with endometriosis and 10 patients without endometriosis served as control. The endometriosis was diagnosed by symptoms, pelvic and transvaginal ultrasound examinations. The serum estrogen levels, fertilization rate and implantation rate were determined. Since the presence of a haemorrhagic cyst was suspected at the ultrasonographic finding of masses parallel to the ovaries, measurement of the CA 125 marker was carried out for differential diagnosis. The data were recorded in Excel sheets and analysed using statistical functions of Excel. The significance level was set at 0.05%. Most of the patients in endometriosis group (68%) had elevated CA125 Levels and 56 % had high E 2 level. In the control, only one patient had high E2 level. In the endometriosis group, 31.67% had positive pregnancy test, while 90% patients without endometriosis had positive pregnancy test. These differences were statistically significant. These data reveal that the patients with endometriosis had significantly higher levels of E2 and CA125 marker in blood and had significantly lower implantation rates as compared to those in the control group.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.013
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.013
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.358
Teacher spread0.337 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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