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Record W4312653853 · doi:10.22374/cjgim.v17i1.544

Maternal Metastatic Synovial Sarcoma in Pregnancy

2022· article· en· W4312653853 on OpenAlexaffvenue
Maureen Okonkwo, Alison Wallace, Bruce Colwell, Kyle McCoy, Nabha Shetty, Ashley Miller, Chris Nash

Bibliographic record

VenueCanadian Journal of General Internal Medicine · 2022
Typearticle
Languageen
FieldMedicine
TopicCancer Risks and Factors
Canadian institutionsDalhousie University
Fundersnot available
KeywordsMedicinePregnancyGestationGynecologyMalignancySarcomaCancerMetastasisInternal medicinePathology

Abstract

fetched live from OpenAlex

Pregnancy with known metastatic cancer is rare. A case of a woman with known metastatic synovial sarcoma in pregnancy is presented in the study. Her disease progressed with an enlarging and new pulmonary metastasis requiring bilateral pulmonary metastasectomies, both during pregnancy and after delivery. Her pregnancy was uncomplicated otherwise, and she had a successful at term vaginal delivery of a healthy female baby. During her second pregnancy, her disease aggressively recurred at eight weeks gestation without therapeutic options. Thus, palliative care was initiated and she died shortly thereafter. The implications of sarcoma growth and the potential thromboembolic risk with active malignancy in pregnancy is discussed in the study. RésuméLa grossesse accompagnée d’un cancer métastatique connu est rare. Cette étude présente le cas d’une femme enceinte atteinte d’un sarcome synovial métastatique connu. Sa maladie a progressé sous forme d’une nouvelle métastase pulmonaire en croissance nécessitant une métastasectomie pulmonaire bilatérale pratiquée pendant la grossesse et après l’accouchement. Sa grossesse s’est déroulée sans autre complication et elle a accouché à terme par voie vaginale d’une fille en bonne santé. Au cours de sa deuxième grossesse, son cancer a récidivé de manière agressive à huit semaines de grossesse sans qu’aucune option thérapeutique ne soit possible. Par conséquent, des soins palliatifs ont été mis en place et elle est décédée peu de temps après. Cette étude exam-ine les conséquences de la croissance du sarcome et le risque thromboembolique potentiel lié aux tumeurs malignes actives durant la grossesse.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.163
Threshold uncertainty score0.995

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.300
Teacher spread0.269 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes2
Has abstractyes

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