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Cognitive impairment as a sequel to SARS-CoV-2 infection

2022· article· en· W4312677245 on OpenAlexaboutno aff
A Rosas Trujillo, F Casarín López, V Baltazar Chávez, V Peláez Hernández, A Orea Tejeda, C D Ledesma Ruíz, N Camácho Mendoza

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicLong-Term Effects of COVID-19
Canadian institutionsnot available
Fundersnot available
KeywordsMontreal Cognitive AssessmentCognitionMedicineCognitive impairmentObservational studyCoronavirus disease 2019 (COVID-19)Internal medicinePsychiatryDisease

Abstract

fetched live from OpenAlex

Introduction: COVID-19 survivor patients report a complaint subjectively related to memory and attention-concentration problems when carry out their daily activities. Objective: To investigate the presence of cognitive sequelae associated with COVID-19. Method: An observational cross-sectional study was conducted. Participated 229 COVID-19 survivor patients, who were evaluated with Montreal Cognitive Assessment (MoCA) and classified into three groups: a) severe cognitive impairment (G1, <13points, n=11), b) mild cognitive impairment (G2, 13-21 points, n=34), and c) without cognitive alterations (G3, 22-30 points, n=184). Statistical analyses were performed in SPSS V25. Results: Average age and male sex: G1: 67.36±10.71, 63.6%; G2: 58.76±11.55, 61.8%; G3: 53.32±11.39, 58.7%. G1 presented statistically differences (p <0.001) in all cognitive functions with the other groups (G1, G2, G3): visuospatial/executive ability (0.09±0.30, 0.53±0.50, 0.83±0.38), identification (2.00±0.89, 2.82±0.38, 2.92±0.32), attention (2.45±0.82, 3.97±1.16, 5.02±0.97), repetition (0.18±0.40, 0.29±0.46, 1.02±0.79), fluency (0.18±0.40, 0.68±0.47, 0.93±0.24), abstraction (0.18±0.40, 0.68±0.72, 1.41±0.77), deferred remembering (0.73±1.10, 1.44±1.37, 3.13±1.36) and orientation (4.64±0.92, 5.35±0.73, 5.79±0.49); except in executive ability, identification, repetition, abstraction and deferred remembering with respect to G2 (p<0.05). Conclusions: Cognitive alterations were found in patients post- COVID, especially in attention and deferred remembering, which could be related to errors of execution in other areas. In the case of the severe cognitive impairment, age may be a related variable. Necessary integrate this variable in the rehabilitation plan for a better prognosis and quality of life of patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.352
Teacher spread0.328 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations1
Published2022
Admission routes1
Has abstractyes

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