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Record W4312833903 · doi:10.22374/cjgim.v16i3.487

Transient Mucor circinelloides fungemia

2021· article· en· W4312833903 on OpenAlexaffvenue
Nicole Veltri, Prameet M. Sheth, Nicole Le Saux

Bibliographic record

VenueCanadian Journal of General Internal Medicine · 2021
Typearticle
Languageen
FieldMedicine
TopicAntifungal resistance and susceptibility
Canadian institutionsUniversity of OttawaQueen's University
Fundersnot available
KeywordsMucor circinelloidesMedicineFungemiaAmphotericin BMucormycosisBlood cultureMucorMicrobiologyImmunologyPathologyMycosisAntibioticsDermatologyBiologyAspergillus

Abstract

fetched live from OpenAlex

Mucor circinelloides is a filamentous fungus that causes rare but devastating human infections. It is also a known human colonizer and laboratory contaminant which is tough to grow in blood culture. We present a case of a 48-year-old male presenting with fever, confusion, and hemodynamic instability, ultimately drug-related, complicated by transient M. circinelloides fungemia. Blood cultures drawn on separate occasions grew M. circinelloides following clinical improvement, likely from intravenous drug use versus nasal septal fracture with the colonization of nasal turbinates. No infectious focus was identified. He received 4 days of liposomal amphotericin B and was discharged home after prolonged observation. This case is a reminder that diagnosis of Zygomycetes infection is based on evidence of tissue invasion and that its growth in blood cultures should be taken seriously, however, it is a poor predictor of the true infection.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.349
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.286
Teacher spread0.260 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2021
Admission routes2
Has abstractyes

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