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A Miniaturized and Automated eDNA Sampler: Application to a Marine Environment

2022· article· en· W4313028256 on OpenAlexafffundabout
Andre Hendricks, Connor Mackie, Edward Luy, Colin Sonnichsen, Lee A. Miller, Mark Wright, Iain Grundke, James T. Smith, Joshua Creelman, Mahtab Tavasoli, Arnold Furlong, Robert G. Beiko, Julie LaRoche, Vincent J. Sieben

Bibliographic record

VenueOCEANS 2022, Hampton Roads · 2022
Typearticle
Languageen
FieldEnvironmental Science
TopicEnvironmental DNA in Biodiversity Studies
Canadian institutionsDalhousie University
FundersCanada First Research Excellence FundMitacsNational Research Council
KeywordsEnvironmental DNASample (material)Protocol (science)Aquatic environmentBiodiversityComputer scienceEnvironmental scienceSampling (signal processing)Filter (signal processing)EcologyBiology

Abstract

fetched live from OpenAlex

Environmental DNA (eDNA) analysis offers a time-and cost-efficient method to perform temporal and spatial observations of aquatic environments, providing a wealth of biodiversity data. Unfortunately, most protocols require manual collection of eDNA samples using highly skilled individuals to capture, filter and store the samples before they can be sent to a lab for analysis. Automated samplers exist to reduce this front-end collection burden, but they tend to be bulky and costly. Here we describe an eDNA sampler designed to be user-friendly and to automate the entire sample collection process. We describe and characterize our eDNA sampler, which offers multi-sample capture, preservation, and self cleaning to reduce cross contamination. DNA sequencing was performed on samples collected using the eDNA sampler as well as a traditional niskin bottle-based protocol at six stations in Bedford Basin, Nova Scotia, Canada. The two approaches showed similar algal and bacterial taxonomic compositions, demonstrating the ability of the eDNA sampler to generate results comparable to those obtained through gold-standard protocols.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.257
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.003
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0100.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.194
Teacher spread0.189 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2022
Admission routes3
Has abstractyes

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Same venueOCEANS 2022, Hampton RoadsSame topicEnvironmental DNA in Biodiversity StudiesFrench-language works237,207