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Record W4313200628 · doi:10.1016/j.nsa.2022.100289

Effect of cariprazine on quality of life and attention in patients with persistent negative symptoms of schizophrenia – a post-hoc analysis

2022· article· en· W4313200628 on OpenAlexaff
T. Oluboka, Andrea Bardell, Howard C. Margolese, Philip G. Tibbo, L. Buchy, C. Di Cresce, R.S. McIntyre

Bibliographic record

VenueNeuroscience Applied · 2022
Typearticle
Languageen
FieldMedicine
TopicSchizophrenia research and treatment
Canadian institutionsABB (Canada)University of TorontoDalhousie UniversityUniversity of OttawaOttawa HospitalUniversity of British ColumbiaMcGill UniversityUniversity of VictoriaUniversity of Calgary
Fundersnot available
KeywordsPost-hoc analysisSchizophrenia (object-oriented programming)PsychologyPost hocNegative symptomClinical psychologyPsychiatryMedicinePsychosisInternal medicine

Abstract

fetched live from OpenAlex

answered by a panel of experts made up of 42 spanish psychiatrists dedicated to the field of study.In thematic area 1 (clinical symptomatology), a consensus was reached in 14 of the 17 items (82.4%).In topic area 2 (treatment factors), consensus was reached on 14 of the 16 items (87.5%).In subject area 3 (healthcare system and sociosanitary services), consensus was reached on all 14 items in the area (100%).In thematic area 4 (physical health and monitoring), a consensus was reached in the 14 items of the area (100%), and in thematic area 5 (clinical care in pandemia) there was also full agreement in the 3 items of the area.A broad consensus has been reached in relation to adapting the treatment of patients with schizophrenia admitted to inpatient units of psychiatry, in carrying out complementary health tests that assess the physical health of schizophrenia patients (electrocardiogram, complete blood count, cholesterol, triglycerides, glycated hemoglobin, liver and kidney function, thyroid hormones, prolactin, etc), implementing simple and well-tolerated regimens, and adapting admission units to pandemic situations (1).Less consensus has been evidenced regarding considering discharge from the psychiatric inpatient units in patients who express distancing from thoughts of suicide, and when they present negative and cognitive symptoms, these being areas that require further investigation.No consensus has been reached either that family associations participate in the care process of the psychiatric inpatients unit and that psychosocial resources have access to the Electronic Medical Record.The COVID-19 pandemic has created challenges for mental health professionals who provide care to patients with schizophrenia in psychiatric inpatient units.The group of experts highlighted the suitability of using telemedicine resources to facilitate regular patient-family and team-reference care circuit contact.Concerns for psychiatric inpatient units include the management of patients and staff who may have been exposed to COVID-19, and the implementation and monitoring of protocols that deal with the clinical care of inpatients with schizophrenia (2).References

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.020

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.004
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0030.004
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0060.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.276
Teacher spread0.265 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2022
Admission routes1
Has abstractno

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