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Record W4313321113 · doi:10.32920/21740804.v1

A primary SERS-active interconnected Si-nanocore network for biomolecule detection with plasmonic nanosatellites as a secondary boosting mechanism

2022· preprint· en· W4313321113 on OpenAlexaff
Jeffery Alexander Powell, Krishnan Venkatakrishnan, Bo Tan

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldNursing
TopicSelenium in Biological Systems
Canadian institutionsSt. Michael's HospitalToronto Metropolitan University
Fundersnot available
KeywordsNanostructureBiomoleculeNanotechnologyBiosensorMaterials sciencePlasmonSurface plasmon resonanceNanomaterialsNoble metalNanoparticleMetalOptoelectronics

Abstract

fetched live from OpenAlex

<p>We report in this study, the development of a polymorphic biosensitive Si nanocore superstructure as a SERS biosensing platform. The polymorphic Si nanostructure in this study is created through ultrafast pulse laser ion-plume (UPLIP) formation and we observe enhanced detection of L-glutathione (GSH). The distinctive polymorphic nanomaterial chemistry of the interconnected network of Si nanocores and the nanonetwork architecture of this nanostructure act as a primary enhancement booster (EF similar to 6 x 10(3)). With the addition of Au/AuPd nanosatellites onto the surface of the polymorphic Si nanocore structure, a significant secondary boost in GSH enhancement is observed (EF similar to 1 x 10(5)). The addition of noble metal nanostructures results in multi-source SERS enhancement that combines linked resonance enhancement and SPR mechanisms that both contribute to the detection and boosting of the biomolecule analyte signal. With this polymorphic Si primary booster and noble metal nanosatellite secondary booster, we have demonstrated the viability of Si nanostructures for SERS biosensing applications.</p> <p> </p>

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.056
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.253
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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