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Record W4313396529 · doi:10.1142/s0218339023500055

<i>IN-SILICO</i> PERFORMANCE INVESTIGATION OF NANOPARTICLE-ASSISTED PHOTO THERMAL ABLATION

2022· article· en· W4313396529 on OpenAlex
Torikul Islam, Md Rejvi Kaysir, Md Jahirul Islam, Sabiha Binte Aziz, Taskia Nadriba Mimma, NASRIN AKTHER

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJournal of Biological Systems · 2022
Typearticle
Languageen
FieldEngineering
TopicPhotoacoustic and Ultrasonic Imaging
Canadian institutionsUniversity of Waterloo
Fundersnot available
KeywordsMultiphysicsAblationMaterials scienceNanoparticleTumor ablationSolverNanotechnologyFluenceFinite element methodCancer treatmentBiomedical engineeringComputer scienceCancerLaserOpticsMedicineAerospace engineeringEngineeringPhysics

Abstract

fetched live from OpenAlex

In recent days, the number of cancer cases is escalating promptly around the world. In general, conventional ablation methods, encompassing comprehensive drawbacks, are employed to cure cancer. At present, photo thermal therapy (PTT) is showing great promise to the treatment of cancer. However, the effective implementation of this technology is utmost challenging as several parameters affect the tumor surroundings. In this work, the effects of different parameters on the performance of PTT have been thoroughly investigated by considering a realistic model of human tissue underneath the skin using a finite element solver, COMSOL Multiphysics. Two different conditions, with and without considering gold nanoparticles at tumor site, are investigated where a laser beam is used as a source of energy. Fluence rate, temperature distribution, and thermal damage are highlighted in this work. It is observed that by utilizing a miniature needle with integrated waveguide and gold nanoparticles, a tumor can be effectively eradicated along with assuaging the conventional drawbacks of PTT. This study would also be useful for designing operative PTT for different parts of human tissue.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.674
Threshold uncertainty score0.209

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.206
Teacher spread0.185 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it