Vasculitis por cocaína-levamisol, manifestaciones cutáneas, articulares y gastrointestinales: reporte de caso
Bibliographic record
Abstract
El levamisol es un antiparasitario de uso veterinario que actualmente está siendo empleado para aumentar el volumen y la potencia de la cocaína y así obtener más ganancias en su comercialización. La mezcla de estas dos sustancias puede causar el síndrome por cocaína-levamisol, caracterizado por lesiones propias de la cocaína como la afección del cartílago septal y perforación del tabique nasal, vasculitis cutánea de pequeños vasos, así como un compromiso vasculítico específico de los pabellones auriculares y del cartílago nasal, que puede avanzar a necrosis e incluso ulceración asociada a agranulocitosis, artralgias y, algunas veces, glomerulonefritis . Se describe un paciente con vasculitis asociada a síndrome por cocaína-levamisol con manifestaciones cutáneas y articulares, además de gastrointestinales. El paciente presentó una respuesta adecuada al manejo con esteroides, pero ante la recurrencia requirió manejo adicional con ciclofosfamida para control total de los síntomas
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.002 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".