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CsCuAO1 associated with CsAMADH1 confers drought tolerance by modulating GABA levels in the tea plant

2023· preprint· en· W4313783089 on OpenAlexaff
Xujun Zhu, Yu Cao, Kexin Zhang, Yi-Wen Chen, Yu Duan, Zhongwei Zou, Qiang Shen, Yuanchun Ma, WANPING FANG

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldAgricultural and Biological Sciences
TopicGABA and Rice Research
Canadian institutionsWilfrid Laurier University
FundersPriority Academic Program Development of Jiangsu Higher Education InstitutionsNational Natural Science Foundation of China
KeywordsNicotiana benthamianaPutrescineDrought toleranceArabidopsisGenetically modified cropsBiologygamma-Aminobutyric acidReactive oxygen speciesTransgenePolyamineTransporterCell biologyBiochemistryBotanyGeneMutantEnzyme

Abstract

fetched live from OpenAlex

Our previous study has shown that copper-containing amine oxidase ( CuAO ) and aminoaldehyde dehydrogenase ( AMADH ) could regulate the accumulation of γ-aminobutyric acid (GABA) in tea plants by participating in polyamine degradation pathway. However, the involvement of these genes in drought tolerance has not been underlined. In this study, CsCuAO1 associated with CsAMADH1 confers drought tolerance, which modulates GABA levels in tea plants, was conducted. The results showed that exogenous GABA spraying effectively alleviated the drought induced physical damage. Overexpression Arabidopsis lines of CsCuAO1 and CsAMADH1 exhibited enhanced resistance to drought, which promoted the synthesis of GABA and putrescine, by alerting reactive oxygen species scavenging capacity and stomatal movement. However, suppression of CsCuAO1 or CsAMADH1 in tea plants exhibited increased sensitivity during drought treatment. Moreover, the co-overexpressed plants increased the accumulation of GABA both in the Agrobacterium -mediated Nicotiana benthamiana transient assay and transgenic Arabidopsis plants. In addition, a GABA transporter, CsGAT1 , was identified, whose expression is strongly correlated with GABA accumulation levels in different tissues under drought stress. Taken together, CsCuAO1 and CsAMADH1 were involved in response to drought stress through a dynamic balance between GABA and putrescine. Our data will greatly contribute to the characterization of GABA biological functions in response to environmental stresses in plants.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.646
Threshold uncertainty score0.541

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.102
GPT teacher head0.280
Teacher spread0.178 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2023
Admission routes1
Has abstractyes

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