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Record W4313815870 · doi:10.18280/ijdne.170618

Review on Curcumin Compounds in Turmeric Plants for the Treatment of COVID-19

2022· article· en· W4313815870 on OpenAlexvenueno aff
Rizal Irfandi, Muhammad Ilham, Erwing Erwing, Ruslang, Muhammad Arafah, Andi Badli Rompegading, Suriati Eka Putri, Suriana Dwi Sartika, Siti Fauziah, Ayu Safitri Agustina, Hairil Akbar, Ahmad Fudholi

Bibliographic record

VenueInternational Journal of Design & Nature and Ecodynamics · 2022
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCurcumin's Biomedical Applications
Canadian institutionsnot available
Fundersnot available
KeywordsCurcuminVirusCoronavirus disease 2019 (COVID-19)CoronavirusVirologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MedicineDiseaseInfectious disease (medical specialty)PharmacologyPathology

Abstract

fetched live from OpenAlex

Coronavirus Disease (COVID-19) is an infectious disease that has a high fatality rate and is spreading quickly throughout the world. The WHO claims that SARS-CoV-2, a brand-new coronavirus strain, is to blame for this outbreak (Severe Acute Respiratory Syndrome Corona Virus-2) and that COVID-19 must be treated with both conventional medical therapy and a combination of modern medicine. The technique of this study, a review of the literature, focused on numerous investigations looking at the potential of curcumin molecules from turmeric to cure the COVID-19 disease. Primary data for scientific papers is gathered from national and international journals through searches on electronic search engines like Google Scholar, Sciencedirect, or PubMed and selected publications are assessed, evaluated, and interpreted by authors. Turmeric contains substances that are immune system boosters, anti-inflammatory, antitumor, antiviral, and antioxidants. Curcumin may prevent a number of viral infections, according to evidence. In vitro testing has shown that the SARS-CoV virus is resistant to curcumin's antiviral properties. It's possible that curcumin can halt viral replication. Curcumin has the potential to treat COVID-19 effectively. Curcumin has antiviral activity that can fight the SARS-CoV-two virus. Treatment with curcumin can change the virus top protein structure, preventing the virus from entering the body and from budding. Future study on the use of curcumin as SARS-Cov-2 virus inhibitory agent is necessary in order to employ it as a novel and long-lasting therapy option for COVID-19 patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.008
Threshold uncertainty score0.026

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.002
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0080.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.322
Teacher spread0.302 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2022
Admission routes1
Has abstractyes

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