Acute infectious purpura fulminans
Bibliographic record
Abstract
Introduction: Acute infectious purpura fulminans is a rare life-threatening complication of sepsis, which rapidly progresses to acute circulatory failure due to intravascular thrombosis and extensive haemorrhagic purpura associated with disseminated intravascular coagulation and multiple organ failure.Case report: A 43-year-old man reported to the emergency room because of dyspnoea following traumatic splenectomy.On admission, the patient reported malaise, fever and chills.The incident happened within a few hours to the development of septic shock.A dermatological examination revealed bleeding spots that did not blanch under pressure, localized mainly on the face and genitals.Empirical antibiotic therapy with vancomycin, cefotaxime and metronidazole was initiated, and then the antibiotic therapy was changed to ceftriaxone.There was a rapid progression that required an amputation of the lower legs.Conclusions: Acute infectious purpura fulminans is a life-threatening disease that requires intensive treatment, but early cutaneous manifestations may facilitate diagnosis and appropriate management.Key words: acute infectious purpura fulminans,
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.004 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.003 | 0.002 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.002 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.002 |
| Insufficient payload (model declined to judge) | 0.021 | 0.013 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".