PRIDE syndrome with lumbosacral hypertrichosis
Bibliographic record
Abstract
Introduction:The PRIDE (Papulopustules and/or paronychia, Regulatory abnormalities of hair growth, Itching, Dryness due to EGFR inhibition) syndrome is a cutaneous adverse effect of EGFR inhibitors. Case report:We describe an 80-year-old man, who presented with itchy papules over the suprapubic region and hair growth over the lower back for 1 month.He was diagnosed with squamous cell carcinoma of the lung, and was treated with oral gefitinib 250 mg daily for 4 months.Cutaneous examination revealed generalized xerosis, discrete papules and pustules with overlying yellow crusts over the suprapubic region, and paronychia with dystrophic changes over the right first and third toe nail.Localised hypertrichosis was seen over the back in midline lumbosacral region.Conclusions: Hair overgrowth such as trichomegaly and hypertrichosis have been described in the PRIDE syndrome.We describe an atypical presentation of the syndrome with lumbosacral hypertrichosis.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.002 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.002 |
| Insufficient payload (model declined to judge) | 0.013 | 0.004 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".