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Record W4317556587 · doi:10.5281/zenodo.7554539

Persistent T cell unresponsiveness associated with chronic VL disease in VL-HIV patients

2023· article· en· W4317556587 on OpenAlexaff
Nicky de Vrij, Antônio Mauro Rezende, Julia Pollmann, Ana Victoria Ibarra Meneses, Thao‐Thy Pham, Wasihun Hailemichael, Mekebib Kassa, Tadfe Bogale, Roma Melkamu, Arega Yeshanew, Rezika Mohammed, Ermias Diro, Ilse Maes, Malgorzata A. Domagalska, Hanne Landuyt, Florian Vogt, Saskia van Henten, Kris Laukens, Bart Cuypers, Pieter Meysman, Hailemariam Beyene, Kasaye Sisay, Aderajew Kibret, Dagnew Mersha, Koert Ritmeijer, Johan van Griensven, Wim Adriaensen

Bibliographic record

VenueZenodo (CERN European Organization for Nuclear Research) · 2023
Typearticle
Languageen
FieldImmunology and Microbiology
TopicImmunodeficiency and Autoimmune Disorders
Canadian institutionsUniversité de Montréal
Fundersnot available
KeywordsMedicineDiseaseHuman immunodeficiency virus (HIV)ImmunologyVirologyInternal medicine

Abstract

fetched live from OpenAlex

Data for "Persistent T cell unresponsiveness associated with chronic VL disease in VL-HIV patients" Data directory Contains processed single-cell RNA and TCR sequencing of two individuals per group. Patient and grouping information is provided in meta_data.txt Script directories src Contains various scripts used to generate the results and figures in the manuscript. Result directories results Contains the inbetween files for many of the analyses. Contains the Seurat object for the single cell analysis reported in the paper. Also used as output directory for the scripts listed in src, thus containing the figures used in the manuscript.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.034
Threshold uncertainty score0.113

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0340.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.206
Teacher spread0.191 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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