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Record W4318169106 · doi:10.1111/nyas.14957

Positive‐strand RNA viruses—a Keystone Symposia report

2023· article· en· W4318169106 on OpenAlexaff
Jennifer Cable, Mark R. Denison, Margaret Kielian, William T. Jackson, Ralf Bartenschlager, Tero Ahola, Suchetana Mukhopadhyay, Daved H. Fremont, Richard Kühn, Ashleigh Shannon, Meredith N. Frazier, Kwok‐Yung Yuen, Carolyn B. Coyne, Katja C. Wolthers, Guo‐li Ming, Jasmine Moshiri, Sonja M. Best, John W. Schoggins, Kellie A. Jurado, Gregory D. Ebel, Alexandra Schäfer, Lisa F. P. Ng, Marjolein Kikkert, Alessandro Sette, Eva Harris, Peter A. C. Wing, Julie Eggenberger, Siddharth R. Krishnamurthy, Marcus G. Mah, Rita M. Meganck, Donghoon Chung, Sebastian Maurer‐Stroh, Raul Andino, Bette Korber, Stanley Perlman, Pei‐Yong Shi, Montserrat Bárcena, Sophie‐Marie Aicher, Michelle N. Vu, Devin Kenney, Brett D. Lindenbach, Yukiko Nishida, Laurent Rénia, Evan P. Williams

Bibliographic record

VenueAnnals of the New York Academy of Sciences · 2023
Typearticle
Languageen
FieldMedicine
TopicViral Infections and Vectors
Canadian institutionsInstitute of Infection and Immunity
FundersNHLBI Division of Intramural ResearchNational Center for Advancing Translational SciencesNational Medical Research CouncilMedical Research CouncilU.S. Food and Drug AdministrationNational Institutes of HealthBiomedical Research CouncilGlobal Health Innovative Technology FundAgency for Science, Technology and ResearchNational Institute of Allergy and Infectious DiseasesDivision of Intramural Research, National Institute of Allergy and Infectious Diseases
KeywordsVirologyRNARNA virusZika virusBiologyCoronavirus disease 2019 (COVID-19)OutbreakPandemicSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirusMedicineGeneticsInfectious disease (medical specialty)

Abstract

fetched live from OpenAlex

Positive-strand RNA viruses have been the cause of several recent outbreaks and epidemics, including the Zika virus epidemic in 2015, the SARS outbreak in 2003, and the ongoing SARS-CoV-2 pandemic. On June 18-22, 2022, researchers focusing on positive-strand RNA viruses met for the Keystone Symposium "Positive-Strand RNA Viruses" to share the latest research in molecular and cell biology, virology, immunology, vaccinology, and antiviral drug development. This report presents concise summaries of the scientific discussions at the symposium.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.013
Threshold uncertainty score0.042

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0040.003
Open science0.0010.003
Research integrity0.0030.004
Insufficient payload (model declined to judge)0.0130.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.136
GPT teacher head0.397
Teacher spread0.261 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2023
Admission routes1
Has abstractyes

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Same venueAnnals of the New York Academy of SciencesSame topicViral Infections and VectorsFrench-language works237,207