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Record W4319861842 · doi:10.1002/047084289x.rn02505

<i>N</i> ‐Isopropyl‐ <i>N</i> ,2‐dimethylpropan‐2‐amine

2023· other· he· W4319861842 on OpenAlexaff
Yann Pauvert

Bibliographic record

VenueEncyclopedia of Reagents for Organic Synthesis · 2023
Typeother
Languagehe
FieldPharmacology, Toxicology and Pharmaceutics
TopicFluorine in Organic Chemistry
Canadian institutionsUniversité de Montréal
Fundersnot available
KeywordsChemistryIsopropylFormaldehydeReagentFormic acidAmine gas treatingMedicinal chemistrySteric effectsBoiling pointPentaneGlyoxalBoilingNuclear chemistryOrganic chemistry

Abstract

fetched live from OpenAlex

[85523-00-8] C 8 H 19 N (MW 129.25) InChI = 1S/C8H19N/c1-7(2)9(6)8(3,4)5/h7H,1-6H3 InChIKey = WYLLBTPEHIVUKV-UHFFFAOYSA-N (sterically hindered and nonnucleophilic tertiary amine, electron donor reagent in photoredox reactions) Alternative Names: N -isopropyl- N -methyl- tert -butylamine, tert- butylisopropylmethylamine; i PM t BA. Preparation: i PM t BA could be prepared by the condensation of the secondary tert- butylisopropylamine (1 equiv) with formaldehyde (1.1 equiv) in the presence of formic acid (1.8 equiv) at 50–55 °C for 2 h. The mixture was neutralized with 8 M aq. KOH (1.5 equiv), extracted with pentane, dried over MgSO 4 , filtered, and distilled, yielding 80%. 1 Physical Data: d 25 °C 0.767 g cm −1 ; boiling point 127 °C. 1 Form Supplied in: commercially available as a colorless liquid.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.006
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.234
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.006
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0030.001
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0020.001
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.1620.015

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.052
GPT teacher head0.366
Teacher spread0.314 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

Explore more

Same venueEncyclopedia of Reagents for Organic SynthesisSame topicFluorine in Organic ChemistryFrench-language works237,207