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Record W4320718790 · doi:10.21203/rs.3.rs-2557682/v1

Reference-quality bat genomes illuminate adaptations to viral tolerance and disease resistance

2023· preprint· en· W4320718790 on OpenAlexafffund
Ariadna E. Morales, Yue Dong, Tom Brown, Kaushal Baid, Dimitrios ‐ Georgios Kontopoulos, Victoria Gonzalez, Zixia Huang, Alexis Ahmed, Leon Hilgers, Sylke Winkler, Graham M. Hughes, Xiaomeng Li, Bogdan Kirilenko, Paolo Devanna, Tanya M. Lama, Yomiran Nissan, Martin Pippel, Liliana M. Dávalos, Sonja C. Vernes, Sébastien J. Puechmaille, Stephen J. Rossiter, Yossi Yovel, Joe Prescott, Andreas Kurth, David Ray, Burton K. Lim, Eugene W. Myers, Emma C. Teeling, Arinjay Banerjee, Aaron T. Irving, Michael Hiller

Bibliographic record

VenueResearch Square · 2023
Typepreprint
Languageen
FieldImmunology and Microbiology
Topicinterferon and immune responses
Canadian institutionsUniversity of TorontoUniversity of WaterlooUniversity of British ColumbiaRoyal Ontario MuseumUniversity of Saskatchewan
FundersNatural Sciences and Engineering Research Council of CanadaRobert Koch InstitutInstitut Universitaire de FranceHessisches Ministerium für Wissenschaft und KunstIrish Research CouncilCanadian Institutes of Health ResearchZhejiang UniversityNational Science FoundationUK Research and InnovationScience Foundation IrelandTechnische Universität DresdenKoch Institute for Integrative Cancer Research, Massachusetts Institute of TechnologyInnovation SaskatchewanMax-Planck-GesellschaftDeutsche Forschungsgemeinschaft
KeywordsBiologyImmune systemISG15GenomeGeneDiseaseInflammationPlant disease resistanceImmunologyGeneticsVirology

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.018

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0020.001
Open science0.0000.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0060.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.136
GPT teacher head0.418
Teacher spread0.282 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations10
Published2023
Admission routes2
Has abstractno

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