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Record W4321201271 · doi:10.1016/j.crneur.2023.100079

A framework and resource for global collaboration in non-human primate neuroscience

2023· review· en· W4321201271 on OpenAlex
Renée Hartig, P. Christiaan Klink, Zlata Polyakova, Mohammad‐Reza A. Dehaqani, Igor Bondar, Hugo Merchant, Wim Vanduffel, Anna Wang Roe, Atsushi Nambu, M. Thirumala, Amir Shmuel, Vishal Kapoor, Katalin M. Gothard, HC Evrard, Michele A. Basso, Christopher I. Petkov, Anna S. Mitchell

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueCurrent Research in Neurobiology · 2023
Typereview
Languageen
FieldVeterinary
TopicAnimal testing and alternatives
Canadian institutionsMcGill UniversityMontreal Neurological Institute and Hospital
FundersNational Institute of Neurological Disorders and StrokeNational Eye InstituteNational Institute on AgingNatural Sciences and Engineering Research Council of CanadaHorizon 2020 Framework ProgrammeNational Institutes of HealthNational Key Research and Development Program of ChinaKU LeuvenFonds Wetenschappelijk OnderzoekNational Natural Science Foundation of ChinaLomonosov Moscow State UniversityWellcome TrustMedical Research CouncilWellcome
KeywordsPromotion (chess)Resource (disambiguation)Diversity (politics)Animal welfarePolitical sciencePsychologyEngineering ethicsPublic relationsKnowledge managementComputer scienceBiology

Abstract

fetched live from OpenAlex

As science and technology evolve, there is an increasing need for promotion of international scientific exchange. Collaborations, while offering substantial opportunities for scientists and benefit to society, also present challenges for those working with animal models, such as non-human primates (NHPs). Diversity in regulation of animal research is sometimes mistaken for the absence of common international welfare standards. Here, the ethical and regulatory protocols for 13 countries that have guidelines in place for biomedical research involving NHPs were assessed with a focus on neuroscience. Review of the variability and similarity in trans-national NHP welfare regulations extended to countries in Asia, Europe and North America. A tabulated resource was established to advance solution-oriented discussions and scientific collaborations across borders. Our aim is to better inform the public and other stakeholders. Through cooperative efforts to identify and analyze information with reference to evidence-based discussion, the proposed key ingredients may help to shape and support a more informed, open framework. This framework and resource can be expanded further for biomedical research in other countries.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.968
Threshold uncertainty score0.976

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.624
GPT teacher head0.654
Teacher spread0.030 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it