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Record W4321793102 · doi:10.1016/j.cccb.2023.100163

Language discordance as a marker of disparities in cerebrovascular risk and stroke outcomes: A multi-center Canadian study

2023· article· en· W4321793102 on OpenAlexafffundabout
Ryan T. Muir, Arunima Kapoor, Megan L. Cayley, Michelle N. Sicard, Karen Lien, Alisia Southwell, Dar Dowlatshahi, Demetrios J. Sahlas, Gustavo Saposnik, Jennifer Mandzia, Leanne K. Casaubon, Ayman Hassan, Yaël Perez, Daniel Selchen, Brian J. Murray, Krista L. Lanctôt, Moira K. Kapral, Nathan Herrmann, Stephen C. Strother, Amy Yu, Peter C. Austin, Susan E. Bronskill, Richard H. Swartz

Bibliographic record

VenueCerebral Circulation - Cognition and Behavior · 2023
Typearticle
Languageen
FieldNeuroscience
TopicNeurobiology of Language and Bilingualism
Canadian institutionsBaycrest HospitalSunnybrook HospitalTrillium Health CentreThunder Bay Regional Health Sciences CentreSunnybrook Health Science CentreSt. Michael's HospitalLondon Health Sciences CentreMcMaster UniversityHamilton General HospitalToronto Western HospitalOttawa HospitalHealth Sciences CentreUniversity Health NetworkHamilton Health SciencesUniversity of Toronto
FundersDepartment of Medicine, University of California, San FranciscoCanadian Institutes of Health ResearchOntario Brain InstituteHeart and Stroke Foundation of Canada
KeywordsMedicineObstructive sleep apneaStroke (engine)ConcordanceInternal medicineDyslipidemiaDepression (economics)Odds ratioSleep apneaDiabetes mellitusRisk factorPhysical therapyObesity

Abstract

fetched live from OpenAlex

Differences in ischemic stroke outcomes occur in those with limited English proficiency. These health disparities might arise when a patient's spoken language is discordant from the primary language utilized by the health system. Language concordance is an understudied concept. We examined whether language concordance is associated with differences in vascular risk or post-stroke functional outcomes, depression, obstructive sleep apnea and cognitive impairment. This was a multi-center observational cross-sectional cohort study. Patients with ischemic stroke/transient ischemic attack (TIA) were consecutively recruited across eight regional stroke centers in Ontario, Canada (2012 – 2018). Participants were language concordant (LC) if they spoke English as their native language, ESL if they used English as a second language, or language discordant (LD) if non-English speaking and requiring translation. 8156 screened patients. 6,556 met inclusion criteria: 5067 LC, 1207 ESL and 282 LD. Compared to LC patients: (i) ESL had increased odds of diabetes (OR = 1.28, p = 0.002), dyslipidemia (OR = 1.20, p = 0.007), and hypertension (OR = 1.37, p<0.001) (ii) LD speaking patients had an increased odds of having dyslipidemia (OR = 1.35, p = 0.034), hypertension (OR = 1.37, p<0.001), and worse functional outcome (OR = 1.66, p<0.0001). ESL (OR = 1.88, p<0.0001) and LD (OR = 1.71, p<0.0001) patients were more likely to have lower cognitive scores. No associations were noted with obstructive sleep apnea (OSA) or depression. Measuring language concordance in stroke/TIA reveals differences in neurovascular risk and functional outcome among patients with limited proficiency in the primary language of their health system. Lower cognitive scores must be interpreted with caution as they may be influenced by translation and/or greater vascular risk. Language concordance is a simple, readily available marker to identify those at risk of worse functional outcome. Stroke systems and practitioners must now study why these differences exist and devise adaptive care models, treatments and education strategies to mitigate barriers influenced by language discordance.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.022
Threshold uncertainty score0.990

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.309
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations10
Published2023
Admission routes3
Has abstractyes

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