MADD-LIKE PATTERN IN PLASMA ACYLCARNITINE PROFILE ASSOCIATED WITH SERTRALINE USE
Bibliographic record
Abstract
El manejo de los estertores de agonía en pacientes con miastenia gravis en situación terminal resulta especialmente complejo. Los fármacos comúnmente empleados en las secreciones respiratorias ruidosas y molestas en los últimos días de vida (escopolamina, buscapina, etc.) pueden precipitar una crisis miasténica por sus efectos anticolinérgicos. Presentamos un caso tratado con octreótido por nuestro equipo, y discutimos las potenciales indicaciones de este fármaco en este contexto.The management of death rattle in patients with terminal myasthenia gravis can be quite complex. Drugs regularly employed to reduce disturbing noisy respiratory secretions (hyoscine hydrobromide, hyoscine butylbromide, etc.) could trigger a myasthenia crisis due to their anti –cholinergic effects. We report a case treated by our team with octreotide, and discuss potential indications in this setting.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".