Antifungal activity of yacon (Smallanthus sonchifolius) extract against candida spp.
Bibliographic record
Abstract
Introduction: Yacon (Smallanthus sonchifolius) is a functional food, rich in fructooligosaccharides, and has been widely used in scientific research, showing effects in reducing lipid and glycemic levels, in addition to having antibacterial, antioxidant and neuroprotective properties. The objective was to evaluate the hydroalcoholic extract of yacon leaf in Candida species. Methods: Thirty-three samples of different species of the genus Candida treated with yacon leaf extract at concentrations of 25 to 400ug/ml were analyzed using the Minimum Inhibitory Concentration method described by the M27-A3 protocol of the Clinical and Laboratory Standards Institute. Results: Among the species of C. albicans, 16 samples showed sensitivity to the extract at the concentrations used. Conclusion: Yeasts of the Candida genus are able to adapt to different environments due to their high degree of resistance to antifungal agents, making it increasingly necessary to use natural substances as alternatives for the treatment of diseases caused by fungi. The antifungal activity of yacon leaf extract against fungi of the genus Candida is being reported for the first time in this study, making yacon a new therapeutic alternative.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.004 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.002 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".