MétaCan
Menu
Back to cohort
Record W4323566265 · doi:10.3389/fsci.2023.1124128

The possible futures of evolutionary medicine

2023· article· en· W4323566265 on OpenAlexaff
Bernard J. Crespi

Bibliographic record

VenueFrontiers in Science · 2023
Typearticle
Languageen
FieldArts and Humanities
TopicPhilosophy and History of Science
Canadian institutionsSimon Fraser University
Fundersnot available
KeywordsFutures contractEvolutionary medicineBiologyEconomicsEvolutionary biologyFinancial economics

Abstract

fetched live from OpenAlex

The future of evolutionary medicine: sparking innovation in biomedicine and public healthThe concept of evolutionary medicine was created about 40 years ago at the University of Michigan's Museum of Zoology when the psychiatrist Randy Nesse walked into the office of Bill Hamilton with a new theory about senescence that was quite wrong.The field thus had a precarious early childhood but was soon guided into strapping adolescence by two works: the 1991 treatise 'Dawn of Darwinian Medicine' by George Williams and Nesse and the 1993 book 'Evolution of Infectious Disease' by Paul Ewald.A string of landmark successes followed: a brilliant monograph on 'Why We Get Sick' by Nesse and Williams, an international society, a thriving Oxford journal, a 'Club EvMed' seminar series led by Charlie Nunn, and a dedicated textbook co-authored by Steve Stearns.It was a paradigm of cross-disciplinary insights, with Randy Nesse tirelessly rallying the troops and Darwin himself taking point.What could possibly go amiss?

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.019
metaresearch head score (Gemma)0.023
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.995
Threshold uncertainty score0.100

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0190.023
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0050.026
Scholarly communication0.0070.014
Open science0.0010.007
Research integrity0.0090.011
Insufficient payload (model declined to judge)0.0150.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.248
Teacher spread0.215 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2023
Admission routes1
Has abstractyes

Explore more

Same venueFrontiers in ScienceSame topicPhilosophy and History of ScienceFrench-language works237,207