A Preliminary Study of Cell Death Dynamics with PFA Using an In Vitro 3D Cardiac Cell Model
Bibliographic record
Abstract
Pulsed field ablation (PFA) has become a promising treatment technique for atrial fibrillation in the recent years. However, the further investigation of the time for characterizing the cardiac cell death after electroporation is required. In this study, five incubation times (0, 3, 6, 12, and 24 h) after electroporation at two different electric field strengths (1000 and 2500 V/cm) were selected to study the dynamics of cell death using an in vitro 3D cardiac cell model. The results achieved in this study demonstrate that the cell death rate changes with the incubation time and the changes are different between the electric field strengths of 1000 and 2500 V/cm. The future work on this difference between the low and high electric fields is warranted using a larger range of electric field strengths.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".