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Record W4324137785 · doi:10.1136/oem-2023-epicoh.154

O-136 New research on the continued health burdens of uranium miners: implications for workers compensation in the United States

2023· article· en· W4324137785 on OpenAlexaff
Kaitlin Kelly‐Reif, Stephen Bertke, Paul A Demers, Jonathan M. Samet, Mary K. Schubauer‐Berigan, Ladislav Tomášek, Lydia B. Zablotska, Charles Wiggins, Estelle Rage, Dominique Laurier, David B. Richardson

Bibliographic record

VenueAbstracts · 2023
Typearticle
Languageen
FieldMedicine
TopicRadiation Dose and Imaging
Canadian institutionsCancer Care Ontario
Fundersnot available
KeywordsMedicineLung cancerEnvironmental healthCohortUraniumCohort studyDemographyGerontologyOncologyPathology

Abstract

fetched live from OpenAlex

Introduction The US Radiation Exposure Compensation Act (RECA) provides compensation to some workers whose health was affected by uranium industry employment. Originally scheduled to terminate in 2022, the US government recently extended RECA benefits for two more years. Another RECA amendment proposes to extend the deadline further, defines additional compensable diseases, and expands eligibility to more contemporary uranium miners. Materials and Methods Researchers at NIOSH conduct extended follow-up on the cohort of US Colorado Plateau uranium miners, and participate in the international Pooled Uranium Miners Analysis (PUMA). Here we apply our recent research findings from both studies to contextualize the health burdens faced by surviving uranium miners, and examine how our research findings relate to the proposed extension and expansion of RECA. Results Former US uranium miners die of silicosis (Standardized Mortality Ratio (SMR)=41.4; 95%CI:30.9–54.3), pneumoconiosis (SMR=39.6; 95%CI:29.3–52.3), idiopathic pulmonary fibrosis (SMR=4.8; 95%CI:3.7–6.1), and lung cancer (SMR=4.5; 95%CI:4.2–4.9) at higher rates than expected. These mortality excesses continue to be observed in recent calendar years. In the PUMA study, uranium miners had higher rates of lung, liver, larynx, stomach, and pleural cancers than expected, and miners hired in later periods also had higher rates of lung and stomach cancer than expected. A positive association between radon exposure and lung cancer mortality is seen in the full PUMA cohort as well as in the sub-cohort of more contemporary miners. Conclusions Recent analyses suggest there be more US uranium miners who develop compensable diseases after the planned termination of RECA benefits in 2024. Uranium miners die at elevated rates from several cancer types that are not currently compensable. Contemporary uranium miners who are ineligible for compensation due to their employment dates experience many of the same health hazards as early-period miners. The proposed amendments to RECA are generally consistent with recent scientific results.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.013
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.040
Threshold uncertainty score0.079

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0070.013
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.002
Science and technology studies0.0010.001
Scholarly communication0.0030.002
Open science0.0010.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0120.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.235
GPT teacher head0.455
Teacher spread0.220 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2023
Admission routes1
Has abstractyes

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