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Record W4324137785 · doi:10.1136/oem-2023-epicoh.154

O-136 New research on the continued health burdens of uranium miners: implications for workers compensation in the United States

2023· article· en· W4324137785 on OpenAlex
Kaitlin Kelly‐Reif, Stephen Bertke, Paul A Demers, Jonathan M. Samet, Mary K. Schubauer‐Berigan, Ladislav Tomášek, Lydia B. Zablotska, Charles Wiggins, Estelle Rage, Dominique Laurier, David B. Richardson

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueAbstracts · 2023
Typearticle
Languageen
FieldMedicine
TopicRadiation Dose and Imaging
Canadian institutionsCancer Care Ontario
Fundersnot available
KeywordsMedicineLung cancerEnvironmental healthCohortUraniumCohort studyDemographyGerontologyOncologyPathology

Abstract

fetched live from OpenAlex

<h3>Introduction</h3> The US Radiation Exposure Compensation Act (RECA) provides compensation to some workers whose health was affected by uranium industry employment. Originally scheduled to terminate in 2022, the US government recently extended RECA benefits for two more years. Another RECA amendment proposes to extend the deadline further, defines additional compensable diseases, and expands eligibility to more contemporary uranium miners. <h3>Materials and Methods</h3> Researchers at NIOSH conduct extended follow-up on the cohort of US Colorado Plateau uranium miners, and participate in the international Pooled Uranium Miners Analysis (PUMA). Here we apply our recent research findings from both studies to contextualize the health burdens faced by surviving uranium miners, and examine how our research findings relate to the proposed extension and expansion of RECA. <h3>Results</h3> Former US uranium miners die of silicosis (Standardized Mortality Ratio (SMR)=41.4; 95%CI:30.9–54.3), pneumoconiosis (SMR=39.6; 95%CI:29.3–52.3), idiopathic pulmonary fibrosis (SMR=4.8; 95%CI:3.7–6.1), and lung cancer (SMR=4.5; 95%CI:4.2–4.9) at higher rates than expected. These mortality excesses continue to be observed in recent calendar years. In the PUMA study, uranium miners had higher rates of lung, liver, larynx, stomach, and pleural cancers than expected, and miners hired in later periods also had higher rates of lung and stomach cancer than expected. A positive association between radon exposure and lung cancer mortality is seen in the full PUMA cohort as well as in the sub-cohort of more contemporary miners. <h3>Conclusions</h3> Recent analyses suggest there be more US uranium miners who develop compensable diseases after the planned termination of RECA benefits in 2024. Uranium miners die at elevated rates from several cancer types that are not currently compensable. Contemporary uranium miners who are ineligible for compensation due to their employment dates experience many of the same health hazards as early-period miners. The proposed amendments to RECA are generally consistent with recent scientific results.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.937
Threshold uncertainty score0.288

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.235
GPT teacher head0.455
Teacher spread0.220 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it