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Record W4328090357 · doi:10.21203/rs.3.rs-2649508/v1

Clinical characteristics of postoperative cognitive dysfunction after local balloon compression for trigeminal neuralgia: a retrospective study

2023· preprint· en· W4328090357 on OpenAlexaboutno aff
Lin Li, Min Liu, He xue

Bibliographic record

VenueResearch Square · 2023
Typepreprint
Languageen
FieldMedicine
TopicTrigeminal Neuralgia and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineMontreal Cognitive AssessmentPostoperative cognitive dysfunctionVisual analogue scaleCognitionAnesthesiaRetrospective cohort studyLocal anesthesiaAnxietyMini–Mental State ExaminationSurgeryCognitive impairmentPsychiatry

Abstract

fetched live from OpenAlex

Abstract Purpose To identify the high-risk population of trigeminal neuralgia (TN) with postoperative cognitive dysfunction, reduce the consequent long-term postoperative complications, and improve the postoperative quality of life. Methods A retrospective study was conducted among 94 TN patients that underwent percutaneous balloon compression in the Affiliated Huai 'an First People's Hospital of Nanjing Medical University from 2017 to 2022. Patients were divided according to the post- Mini-Mental State Examimation (MMSE) scores (postoperative cognitive dysfunction and postoperative cognitive function normal groups). General information, past medical history, laboratory examination, treatment methods, self rating anxiety scale (SAS) score, visual analog scale (VAS) score and MMSE score were collected. Results Total 21 patients developed postoperative cognitive impairment, of which 16 were transient, and 3 were prolonged. Postoperative cognitive impairment prolonged the hospital stay (p< 0.001). Advanced age (p = 0.028), high preoperative SAS score (p < 0.001), and prolonged anesthesia duration (p < 0.032) were independent risk factors for surgical patients of TN. Three patients in the postoperative cognitive dysfunction group showed brain swelling and extensive white matter degeneration in the frontal and parietal lobes. Eight patients were treated with hyperbaric oxygen (HBO), following which, the MMSE score was significantly higher (p < 0.05) than that in the group without HBO, with no long-term complications. Preoperative SAS score was negatively correlated with the postoperative MMSE score (R = 0.3541, p < 0.001). Conclusion Postoperative cognitive dysfunction prolongs hospital stay in patients with TN. Functional magnetic resonance imaging can reflect brain tissue damage, and HBO therapy helps in postoperative cognitive function recovery.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.137
GPT teacher head0.479
Teacher spread0.342 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2023
Admission routes1
Has abstractyes

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