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Record W4328090357 · doi:10.21203/rs.3.rs-2649508/v1

Clinical characteristics of postoperative cognitive dysfunction after local balloon compression for trigeminal neuralgia: a retrospective study

2023· preprint· en· W4328090357 on OpenAlexaboutno aff
Lin Li, Min Liu, He xue

Bibliographic record

VenueResearch Square · 2023
Typepreprint
Languageen
FieldMedicine
TopicTrigeminal Neuralgia and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineMontreal Cognitive AssessmentPostoperative cognitive dysfunctionVisual analogue scaleCognitionAnesthesiaRetrospective cohort studyLocal anesthesiaAnxietyMini–Mental State ExaminationSurgeryCognitive impairmentPsychiatry

Abstract

fetched live from OpenAlex

<title>Abstract</title> Purpose To identify the high-risk population of trigeminal neuralgia (TN) with postoperative cognitive dysfunction, reduce the consequent long-term postoperative complications, and improve the postoperative quality of life. Methods A retrospective study was conducted among 94 TN patients that underwent percutaneous balloon compression in the Affiliated Huai 'an First People's Hospital of Nanjing Medical University from 2017 to 2022. Patients were divided according to the post- Mini-Mental State Examimation (MMSE) scores (postoperative cognitive dysfunction and postoperative cognitive function normal groups). General information, past medical history, laboratory examination, treatment methods, self rating anxiety scale (SAS) score, visual analog scale (VAS) score and MMSE score were collected. Results Total 21 patients developed postoperative cognitive impairment, of which 16 were transient, and 3 were prolonged. Postoperative cognitive impairment prolonged the hospital stay (p&amp;lt; 0.001). Advanced age (p = 0.028), high preoperative SAS score (p &lt; 0.001), and prolonged anesthesia duration (p &lt; 0.032) were independent risk factors for surgical patients of TN. Three patients in the postoperative cognitive dysfunction group showed brain swelling and extensive white matter degeneration in the frontal and parietal lobes. Eight patients were treated with hyperbaric oxygen (HBO), following which, the MMSE score was significantly higher (p &lt; 0.05) than that in the group without HBO, with no long-term complications. Preoperative SAS score was negatively correlated with the postoperative MMSE score (R = 0.3541, p &lt; 0.001). Conclusion Postoperative cognitive dysfunction prolongs hospital stay in patients with TN. Functional magnetic resonance imaging can reflect brain tissue damage, and HBO therapy helps in postoperative cognitive function recovery.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.029
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0010.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.137
GPT teacher head0.479
Teacher spread0.342 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2023
Admission routes1
Has abstractyes

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