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Record W4360620737 · doi:10.33137/utmj.v100i1.39018

A coagulopathic conundrum of COVID-19

2023· article· en· W4360620737 on OpenAlexvenueno aff
Peter Iskander, Jiayi Zheng, Syed Muhammad Hussain Zaidi, Anthony Iskander

Bibliographic record

VenueUniversity of Toronto Medical Journal · 2023
Typearticle
Languageen
FieldMedicine
TopicCOVID-19 Clinical Research Studies
Canadian institutionsnot available
Fundersnot available
KeywordsMedicinePneumoniaIntensive care unitDisseminated intravascular coagulationCoronavirus disease 2019 (COVID-19)Differential diagnosisFibrinogenCryoprecipitateIntubationInternal medicineIntensive care medicineAnesthesiaPathology

Abstract

fetched live from OpenAlex

We present a case of an elderly male who presented to the hospital with a worsening cough and shortness of breath. Previous outpatient COVID-19 polymerase chain reaction test was negative, and the patient’s symptoms failed to improve despite one-week course of antibiotics. He presented to the hospital a few days later with worsening symptoms and a positive COVID-19 polymerase chain reaction test at this time. Patient was febrile, tachycardic, hypertensive, and was admitted to the intensive care unit due to desaturation on room air ultimately leading to intubation. CBC with differential showed evidence of thrombocytopenia, elevated INR/D-Dimer/fibrin split products/inflammatory markers, as well as decreased fibrinogen. He was treated for COVID-19 pneumonia and given platelets/cryoprecipitate/Vit K for suspected diffuse intravascular coagulation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.045
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.391
Threshold uncertainty score0.994

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.045
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0070.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.053
GPT teacher head0.398
Teacher spread0.345 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2023
Admission routes1
Has abstractyes

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