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Record W4360939369 · doi:10.1038/s41409-023-01962-0

Role of Hospital Exemption in Europe: position paper from the Spanish Advanced Therapy Network (TERAV)

2023· letter· en· W4360939369 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

fundA Canadian funder is recorded on the work.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueBone Marrow Transplantation · 2023
Typeletter
Languageen
FieldMedicine
TopicBiomedical Ethics and Regulation
Canadian institutionsnot available
FundersBiocruces Bizkaia es el Instituto de Investigación SanitariaFaculty of Medicine and Health, University of SydneyInstitute for Bioengineering of CataloniaInstituto de Salud Carlos IIICentro Pfizer-Universidad de Granada-Junta de Andalucía de Genómica e Investigación OncológicUniversidad de GranadaMinisterio de Economía y CompetitividadUniversitat de BarcelonaUniversidad Autónoma de MadridInstitut d’Investigacions Biomèdiques August Pi i Sunyer, Universitat de BarcelonaBarcelona Institute of Science and TechnologyUniversidad de NavarraInstitució Catalana de Recerca i Estudis AvançatsUniversidad de MurciaPfizerEuropean CommissionCentro de Investigaciones Energéticas, Medioambientales y TecnológicasCentro de Investigación Biomédica en Red de CáncerCanadian Institute of Steel ConstructionUniversidad de Sevilla
KeywordsMedicinePosition paperPosition (finance)Family medicinePathology

Abstract

fetched live from OpenAlex

The Hospital Exemption rule is considered a valuable European legislative initiative that guarantees patient access to novel therapies based on the use of advanced therapy medicinal products (ATMPs) in the Member States. On the occasion of the update of the European General Pharmaceutical Legislation, the Spanish Network of Advanced Therapies (TERAV, formerly TerCel), which has played a recognized leadership in Europe in the development of both academic and pharmaceutically commercialized ATMPs [ 1 ], would like to make the following position statement:

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Commentary · Consensus signal: none
Teacher disagreement score0.803
Threshold uncertainty score0.689

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.234
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it