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Record W4365519917 · doi:10.1016/s2214-109x(23)00165-1

Prioritising respiratory syncytial virus prevention in low-income and middle-income countries

2023· article· en· W4365519917 on OpenAlexafffund
Xavier Carbonell‐Estrany, Eric A. F. Simões, Louis Bont, Bosco Paes, Adaeze C. Ayuk, Ángela Gentile, Anne Greenough, Antonio Moreno, Arun Kumar Sharma, Asunción Mejías, Barry Rodgers‐Gray, Bernhard Resch, Brigette Fauroux, Carlos E. Rodríguez‐Martínez, Chadi El Saleeby, W. Charles Huskins, Cheryl Cohen, David A. Greenberg, Eugenio Baraldi, Evan J. Anderson, Federico Martinón‐Torres, Fernando F Polack, Giovanni Piedimonte, Harish Nair, Hayley A. Gans, Heather J. Zar, Hiroyuki Moriuchi, Hitoshi Oshitani, Ian Mitchell, D. James Nokes, Sheikh Jarju, Jeffrey M. Pernica, Jesse Papenburg, Joan Robinson, Joanne de Jesus-Cornejo, Joanne M. Langley, Johannes G. Liese, Jose Figueras Aloy, Juan Pablo Torres, Kathryn M. Edwards, Leonard R. Krilov, Maduja Divaratne, Manuel Sánchez Luna, Marcello Lanari, Marcelo Comerlato Scottá, Maria Ahuoiza Garba, M. Mori, Merih Çetınkaya, Mitchell Goldstein, Najwa Khuri‐Bulos, Néstor Vain, Nikolaos G. Papadopoulus, Nusrat Homaira, Octavio Ramilo, Paolo Manzoni, Patrick K. Munywoki, Pedro A. Piedra, Peter P. Moschovis, Peter Openshaw, Quique Bassat, Renato T. Stein, Rik Thwaites, Rohitha Muthugala, Rolando Ulloa‐Gutiérrez, Ron Dagan, Rosa Rodríguez Fernández, Satoshi Kusuda, Shabir A. Madhi, Shobha Broor, Simon B. Drysdale, Sudha Basnet, Terho Heikkinen, Vasanthi Avadhanula, Xavier Sáez‐Llorens, Xin Wang, You Li, Joseph L. Mathew

Bibliographic record

VenueThe Lancet Global Health · 2023
Typearticle
Languageen
FieldMedicine
TopicRespiratory viral infections research
Canadian institutionsMcMaster University
FundersMedical Research CouncilDepartment of Epidemiology, Biostatistics and Occupational Health, McGill UniversityCumming School of Medicine, University of CalgarySwedish Orphan BiovitrumFundació Institut de Recerca Hospital Universitari Vall d’HebronUniversitat Autònoma de BarcelonaUniversity of Cape TownUniversidad de ChileInstituto de Salud Carlos IIIUniversitat de BarcelonaSchool of Medicine, Emory UniversityUniversidad de Buenos AiresBen-Gurion University of the NegevInstitució Catalana de Recerca i Estudis AvançatsNational Institute for Health and Care ResearchUniversity of AlbertaAstraZenecaCidara TherapeuticsUniversidad El BosqueNovavaxTulane UniversityUniversidad Nacional de ColombiaTribhuvan UniversityVanderbilt University Medical CenterWellcome TrustRegeneron PharmaceuticalsLondon School of Hygiene and Tropical MedicineKarl-Franzens-Universität GrazMcGill UniversityEmory UniversityKing's College LondonNational Institute of Environmental Health SciencesMcMaster UniversityVanderbilt UniversityMedizinische Universität GrazDalhousie UniversityGlaxoSmithKlineBill and Melinda Gates FoundationUniversity of WarwickPfizerUniversidade de Santiago de CompostelaSanofi
KeywordsLow and middle income countriesRespiratory systemDeveloping countryMedicineBusinessVirologyEnvironmental healthEconomic growthEconomicsInternal medicine

Abstract

fetched live from OpenAlex

Respiratory syncytial virus is a major cause of lower respiratory tract infection morbidity and mortality in children globally, causing 3·2–3·6 million hospitalisations and more than 100 000 deaths annually in children younger than 5 years, 99% of which occur in low-income and middle-income countries (LMICs).1 Despite being identified 65 years ago, at the same time as poliovirus, there is no widely available and affordable preventive strategy for respiratory syncytial virus.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.011
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.017
Threshold uncertainty score0.047

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.011
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0040.003
Open science0.0020.006
Research integrity0.0040.004
Insufficient payload (model declined to judge)0.0140.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.081
GPT teacher head0.437
Teacher spread0.356 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations26
Published2023
Admission routes2
Has abstractyes

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Same venueThe Lancet Global HealthSame topicRespiratory viral infections researchFrench-language works237,207