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Record W4366422437 · doi:10.1002/cjs.11771

Finite sample and asymptotic distributions of a statistic for sufficient follow‐up in cure models

2023· article· en· W4366422437 on OpenAlexvenueno aff
Ross Maller, Sidney I. Resnick, Soudabeh Shemehsavar

Bibliographic record

VenueCanadian Journal of Statistics · 2023
Typearticle
Languageen
FieldMathematics
TopicStatistical Methods in Clinical Trials
Canadian institutionsnot available
Fundersnot available
KeywordsCensoring (clinical trials)StatisticTest statisticAsymptotic distributionMathematicsStatisticsSample (material)PopulationAsymptotic analysisKaplan–Meier estimatorNull distributionSample size determinationNull hypothesisApplied mathematicsStatistical hypothesis testingEstimatorMedicinePhysics

Abstract

fetched live from OpenAlex

Abstract The existence of immune or cured individuals in a population and whether there is sufficient follow‐up in a sample of censored observations on their lifetimes to be confident of their presence are questions of major importance in medical survival analysis. Here we give a detailed analysis of a statistic designed to test for sufficient follow‐up in a sample. Assuming an i.i.d. censoring model, we obtain exact finite‐sample and asymptotic distributions for the statistic, and use these to calculate the power of a test based on it. A particularly useful finding is that the asymptotic distribution of the test statistic is parameter‐free in the null case when follow‐up is insufficient. The methods are illustrated with application to a glioma cancer dataset.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.197
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.259
Threshold uncertainty score0.810

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.197
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.473
GPT teacher head0.480
Teacher spread0.007 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designTheoretical or conceptual
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2023
Admission routes1
Has abstractyes

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