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Record W4366549233 · doi:10.21203/rs.3.rs-2738526/v1

Health-related quality of life and its predictive factors in patients with systemic lupus erythematosus in southwest Iran: a cross-sectional study

2023· preprint· en· W4366549233 on OpenAlexaff
Sakineh Hashemi, Sahar Farahbakhsh, Zahra Aghakhani, Nazi Hemati, Somayeh Hashemi

Bibliographic record

VenueResearch Square · 2023
Typepreprint
Languageen
FieldMedicine
TopicSystemic Lupus Erythematosus Research
Canadian institutionsYork University
FundersShiraz University
KeywordsMedicineQuality of life (healthcare)Bayesian multivariate linear regressionMultivariate analysisInternal medicineCross-sectional studyMultivariate statisticsSystemic lupus erythematosusDiseasePhysical therapyRegression analysisPathology

Abstract

fetched live from OpenAlex

Abstract Background Quality of life (QoL) is an important measure in health assessment. It is impacted by several factors in Systemic Lupus Erythematosus (SLE) patients which are not entirely clear. This aims of study was evaluation of factors affecting QoL in SLE patients.Methods This cross-sectional study was performed on 140 Iranian SLE patients of Hafiz Hospital. Questionnaire Lupus Quality of Life (LupusQoL) was used to evaluate the quality of life. The patients were evaluated with this questionnaire during 4 weeks in eight dimensions of health, emotional health, body image, pain, planning, intimate relationships and the burden of others. Predictive factors of LupusQoL were evaluated using multivariate linear regression.Results The total mean QoL Score was 65.5 ± 22.4.The highest score of SLE patients' quality of life is related to planning 78.36 ± 25.03 and the lowest score of QoL was related to emotional 54.70 ± 30.51.The results of multivariate analysis showed that duration of disease (β:-1.14, 95% CI:-1.6,-0.61, P:0.001), physical activity(β:-13.2, 95% CI:-20.8,-5.4, P:0.001), kidney involvement (β:-10.38, 95% CI:-17.61,-3.15, P:0.03) and skin involvement(β:-9.5, 95% CI:-18.1,-0.77, P:0.023) were significantly related to the total mean QOL score of SLE patients.Conclusion The findings confirmed that the SLE patients enjoy the middle QoL which can be due to the various factors of disease activity, different bodily systems involvement, and local, cultural, national, and racial aspects.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.127
GPT teacher head0.418
Teacher spread0.291 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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