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Record W4366829895 · doi:10.1002/lio2.1065

<scp>Postoperative</scp> opioid use following head and neck endocrine surgery: A <scp>multi‐center</scp> prospective study

2023· article· en· W4366829895 on OpenAlexaffabout
Amr F. Hamour, Mirko Manojlovic‐Kolarski, Antoine Eskander, Mathew Biskup, Subhashni Taylor, Frédérick Laliberté, Allan Vescan, Ian Witterick, Jeremy L. Freeman, Eric Monteiro

Bibliographic record

VenueLaryngoscope Investigative Otolaryngology · 2023
Typearticle
Languageen
FieldMedicine
TopicOpioid Use Disorder Treatment
Canadian institutionsMount Sinai HospitalDalhousie UniversityToronto East General HospitalPublic Health OntarioUniversity of Toronto
Fundersnot available
KeywordsMedicineOpioidMedical prescriptionProspective cohort studyEndocrine systemAnesthesiaAnalgesicEndocrine surgerySurgeryInternal medicineThyroidHormone

Abstract

fetched live from OpenAlex

Abstract Background Opioid abuse is widespread in North America and the over‐prescription of opioids are a contributing factor. The goal of this prospective study was to quantify over‐prescription rates, evaluate postoperative experiences of pain, and understand the impact of peri‐operative factors such as adequate pain counseling and use of non‐opioid analgesia. Methods Consecutive recruitment of patients undergoing head and neck endocrine surgery was undertaken from January 1st 2020 to December 31st 2021 at four Canadian hospitals in Ontario and Nova Scotia. Postoperative tracking of pain levels and analgesic requirements were employed. Chart review and preoperative and postoperative surveys provided information on counseling, use of local anesthesia, and disposal plans. Results A total of 125 adult patients were included in the final analysis. Total thyroidectomy was the most common procedure (40.8%). Median use of opioid tablets was 2 (IQR 0–4), with 79.5% of prescribed tablets unused. Patients who reported inadequate counseling ( n = 35, 28.0%) were more likely to use opioids (57.2% vs. 37.8%, p &lt; .05) and less likely to use non‐opioid analgesia in the early postoperative course (42.9% vs. 63.3%, p &lt; .05). Patients who received local anesthesia peri‐operatively (46.4%, n = 58) reported less severe pain on average [2.86 (2.13) vs. 4.86 (2.19), p &lt; .05] and used less analgesia on postoperative day one [0 MME (IQR 0–4) vs. 4 MME (IQR 0–8), p &lt; .05]. Conclusion Over‐prescription of opioid analgesia following head and neck endocrine surgery is common. Patient counseling, use of non‐opioid analgesia, and peri‐operative local anesthesia were important factors in narcotic use reduction. Level of evidence Level 3.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.006
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.006
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0010.002
Science and technology studies0.0010.001
Scholarly communication0.0000.001
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.039
GPT teacher head0.303
Teacher spread0.264 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2023
Admission routes2
Has abstractyes

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