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Record W4367053066 · doi:10.1089/neu.2022.0403

North American Clinical Trials Network for Spinal Cord Injury Registry: Methodology and Analysis

2023· article· en· W4367053066 on OpenAlexaff
Elizabeth G. Toups, Beatrice Ugiliweneza, Susan Howley, Chris J. Neal, James S. Harrop, James D. Guest, Robert G. Grossman, Michael G. Fehlings

Bibliographic record

VenueJournal of Neurotrauma · 2023
Typearticle
Languageen
FieldMedicine
TopicSpinal Cord Injury Research
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsClinical trialMedicineSpinal cord injuryRehabilitationNeurosurgeryPhysical therapyMedical emergencySpinal cordSurgeryPsychiatryPathology

Abstract

fetched live from OpenAlex

The North American Clinical Trials Network (NACTN) for Spinal Cord Injury (SCI) is a consortium of neurosurgery departments at university affiliated hospitals with medical, nursing, and rehabilitation personnel who are skilled in the assessment, evaluation, and management of SCI. NACTN was established with the goal of consistently advancing the quality of life of people with SCI through clinical trials of new therapies that provide robust evidence of safety and effectiveness. A prospective multi-center Registry was created to collect the natural course of the acute traumatic SCI patient from time of injury to 12 months follow-up. NACTN's network of hospitals enrolls a significant number of patients, defines and adheres to standard protocols, and provides the infrastructure and highly skilled personnel to conduct trials of therapy for SCI. Registry data have been used by academic institutions and by the biotechnology and pharmaceutical sectors to create comparison datasets for Phase I clinical trials of new therapies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.135
metaresearch head score (Gemma)0.246
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.135
Threshold uncertainty score0.713

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1350.246
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0060.004
Bibliometrics0.0110.020
Science and technology studies0.0010.002
Scholarly communication0.0050.002
Open science0.0050.004
Research integrity0.0020.004
Insufficient payload (model declined to judge)0.0250.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.660
GPT teacher head0.622
Teacher spread0.038 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2023
Admission routes1
Has abstractyes

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Same venueJournal of NeurotraumaSame topicSpinal Cord Injury ResearchFrench-language works237,207