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Record W4367157467 · doi:10.1021/cen-10001-feature1

Mining proteins for crime scene clues

2022· article· en· W4367157467 on OpenAlexaboutno aff
special to C EN Carolyn Wilke

Bibliographic record

VenueC&EN Global Enterprise · 2022
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicVenomous Animal Envenomation and Studies
Canadian institutionsnot available
Fundersnot available
KeywordsToddlerCoronerCriminologyHistoryGenealogyPsychologyMedicinePoison controlMedical emergencySuicide prevention

Abstract

fetched live from OpenAlex

In May 2014, 2-year-old Aleka Gonzales of North Vancouver, British Columbia, died under mysterious circumstances. She had been with a babysitter the day before, and bruising on her body led the coroner to think initially that the toddler had been beaten. But the uniformity of Gonzales’s injuries hinted at a different cause: the babysitter kept exotic pets, and bites from venomous animals can turn skin black and blue. Unable to search the babysitter’s home, police requested help from the local scientific community to identify potential toxins in blood and urine samples collected from the child’s body. Leonard J. Foster, a biochemist at the University of British Columbia, answered the call. He set about analyzing all the proteins in the samples, aiming to capture any peptide or protein toxins present. With information from the police investigators, Foster’s team started to focus its search on snake venom. After removing some of the

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.618
Threshold uncertainty score0.447

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.270
Teacher spread0.260 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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