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Record W4367172219 · doi:10.1101/2023.04.27.538574

Exploring Correlation-Based Brain Networks with Adaptive Signed Random Walks

2023· preprint· en· W4367172219 on OpenAlexaff
Roberto C. Sotero, José M. Sánchez‐Bornot

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2023
Typepreprint
Languageen
FieldNeuroscience
TopicFunctional Brain Connectivity Studies
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsThresholdingRandom walkComputer scienceNode (physics)CognitionArtificial intelligenceCorrelationFunction (biology)Range (aeronautics)Complex networkMathematicsPsychologyNeuroscienceStatisticsPhysics

Abstract

fetched live from OpenAlex

Abstract The human brain is a highly connected network with complex patterns of correlated and anticorrelated activity. Analyzing functional connectivity matrices derived from neuroimaging data can provide insights into the organization of brain networks and their association with cognitive processes or disorders. Common approaches, such as thresholding or binarization, often disregard negative connections, which may result in the loss of critical information. This study introduces an adaptive signed random walk (ASRW) model for analyzing correlation- based brain networks that incorporates both positive and negative connections. The model calculates transition probabilities between brain regions as a function of their activities and connection strengths, dynamically updating probabilities based on the differences in node activity and connection strengths at each time step. Results show that the classical random walk approach, which only considers the absolute value of connections, underestimates the mean first passage time (MFPT) compared to the proposed ASRW model. Our model captures a wide range of interactions and dynamics within the network, providing a more comprehensive understanding of its structure and function. This study suggests that considering both positive and negative connections, has the potential to offer valuable insights into the interregional coordination underlying various cognitive processes and behaviors.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.005
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0010.002
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.077
GPT teacher head0.229
Teacher spread0.152 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2023
Admission routes1
Has abstractyes

Explore more

Same venuebioRxiv (Cold Spring Harbor Laboratory)→Same topicFunctional Brain Connectivity Studies→French-language works237,207→