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Photodynamic and Photothermal Therapies: Synergy Opportunities for Nanomedicine

2023· review· en· 1,212 citations· W4367180472 on OpenAlex· 10.1021/acsnano.3c00891

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Classifier prediction

metacan-v1-d91a1de5be90

Predictions imitate two machine teachers. Scores are not calibrated prevalence probabilities.

Classifier candidate
Bench or experimentalNot applicable
Classifier consensus
N/A
Teacher imitation scores

Codex

Bench or experimental0.028
Other design0.028
Systematic review0.015
Theoretical or conceptual0.005
Not applicable0.004
Meta-analysis0.001
Meta-epidemiology (broad)0.000
Simulation or modelling0.000
Metaresearch0.000
Meta-epidemiology (narrow)0.000
Bibliometrics0.000
Research integrity0.000
Case report0.000
Qualitative0.000
Science and technology studies0.000
Scholarly communication0.000
Non-randomized trial0.000
Open science0.000
Randomized trial0.000
Observational0.000

Gemma

Not applicable0.725
Bench or experimental0.091
Systematic review0.008
Qualitative0.002
Simulation or modelling0.001
Meta-analysis0.001
Scholarly communication0.000
Meta-epidemiology (broad)0.000
Bibliometrics0.000
Open science0.000
Metaresearch0.000
Meta-epidemiology (narrow)0.000
Research integrity0.000
Theoretical or conceptual0.000
Science and technology studies0.000
Randomized trial0.000
Non-randomized trial0.000
Observational0.000
Case report0.000

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.075
GPT teacher head0.292
Teacher spread
0.217 how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

Tumoricidal photodynamic (PDT) and photothermal (PTT) therapies harness light to eliminate cancer cells with spatiotemporal precision by either generating reactive oxygen species or increasing temperature. Great strides have been made in understanding biological effects of PDT and PTT at the cellular, vascular and tumor microenvironmental levels, as well as translating both modalities in the clinic. Emerging evidence suggests that PDT and PTT may synergize due to their different mechanisms of ac…

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