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Record W4367183877 · doi:10.1002/ejhf.2874

Worsening of Chronic Heart Failure: Definition, Epidemiology, Management and Prevention. A Clinical Consensus Statement by the Heart Failure Association of the European Society of Cardiology

2023· article· en· W4367183877 on OpenAlexafffund
Marco Metra, Daniela Tomasoni, Marianna Adamo, Antoni Bayés‐Genís, Gerasimos Filippatos, Magdy Abdelhamid, Stamatis Adamopoulos, Stefan D. Anker, Laura Antohi, Michael Böhm, Frieder Braunschweig, Tuvia Ben Gal, Javed Butler, John G.F. Cleland, Alain Cohen‐Solal, Kevin Damman, Finn Gustafsson, Loreena Hill, Ewa A. Jankowska, Mitja Lainščak, Lars H. Lund, Theresa McDonagh, Alexandre Mebazaa, Brenda Moura, Wilfried Müllens, Massimo Piepoli, Piotr Ponikowski, Amina Rakisheva, Arsen Ristić, Gianluigi Savarese, Petar Seferović, Rajan Sharma, Carlo G. Tocchetti, Mehmet Birhan Yılmaz, Cristiana Vitale, Maurizio Volterrani, Stephan von Haehling, Ovidiu Chioncel, Andrew J.S. Coats, Giuseppe Rosano

Bibliographic record

VenueEuropean Journal of Heart Failure · 2023
Typearticle
Languageen
FieldMedicine
TopicHeart Failure Treatment and Management
Canadian institutionsSurgical Specialties (Canada)
FundersRelypsaAbbott VascularServierStockholms Läns LandstingRespicardiaQueen's UniversityDeutsche ForschungsgemeinschaftUniversity of GlasgowPfizerModernaIdorsia PharmaceuticalsKarolinska InstitutetImpulse DynamicsNovo NordiskMyoKardiaReCor MedicalBritish Heart FoundationVetenskapsrådetCytokineticsEuropean CommissionSanofiGedeon RichterLivaNovaDeutsches Zentrum für Herz-KreislaufforschungQueen's University BelfastBoston Scientific CorporationHelsinnAlnylam PharmaceuticalsBristol-Myers SquibbEli Lilly and CompanyAstraZenecaAmgenChugai PharmaceuticalVifor PharmaMinistero della SaluteAbbott Laboratories
KeywordsMedicineHeart failureIntensive care medicineGuidelineDiureticEpidemiologyInternal medicinePathology

Abstract

fetched live from OpenAlex

Episodes of worsening symptoms and signs characterize the clinical course of patients with chronic heart failure (HF). These events are associated with poorer quality of life, increased risks of hospitalization and death and are a major burden on healthcare resources. They usually require diuretic therapy, either administered intravenously or by escalation of oral doses or with combinations of different diuretic classes. Additional treatments may also have a major role, including initiation of guideline-recommended medical therapy (GRMT). Hospital admission is often necessary but treatment in the emergency service or in outpatient clinics or by primary care physicians has become increasingly used. Prevention of first and recurring episodes of worsening HF is an essential component of HF treatment and this may be achieved through early and rapid administration of GRMT. The aim of the present clinical consensus statement by the Heart Failure Association of the European Society of Cardiology is to provide an update on the definition, clinical characteristics, management and prevention of worsening HF in clinical practice.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.025
metaresearch head score (Gemma)0.023
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.025
Threshold uncertainty score0.131

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0250.023
Meta-epidemiology (narrow)0.0030.001
Meta-epidemiology (broad)0.0040.003
Bibliometrics0.0060.004
Science and technology studies0.0010.003
Scholarly communication0.0040.003
Open science0.0050.004
Research integrity0.0060.010
Insufficient payload (model declined to judge)0.0010.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.052
GPT teacher head0.322
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations183
Published2023
Admission routes2
Has abstractyes

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