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Record W4367276947 · doi:10.1121/10.0018306

Fully electronically steerable high power ultrasound phased arrays for therapy—A review of progress

2023· article· en· W4367276947 on OpenAlexaff
Kullervo Hynynen

Bibliographic record

VenueThe Journal of the Acoustical Society of America · 2023
Typearticle
Languageen
FieldMedicine
TopicTissue Engineering and Regenerative Medicine
Canadian institutionsUniversity of TorontoSunnybrook Health Science Centre
Fundersnot available
KeywordsTransducerPhased arrayAcousticsUltrasoundComputer scienceFocused ultrasoundPower (physics)Energy (signal processing)Focus (optics)Ultrasound energyMaterials scienceBiomedical engineeringOpticsPhysicsTelecommunicationsAntenna (radio)Engineering

Abstract

fetched live from OpenAlex

When combined with imaging-guidance focused ultrasound (FUS) provides means for localized delivery of mechanical energy deep into tissues. This focal energy deposition can modify tissue function via thermal or mechanical interactions with the tissue. Traditionally, ultrasound has been focused using spherically curved phased arrays that allow limited electronic steering around geometric focus of the array. To have a fully electronically steered arrays requires the transducer element size to be < wavelength/2 of the ultrasound wave. One way to accomplish this is to use sparse arrays with small transducer elements, the other is to have fully populated arrays with thousands of elements and required electronic complexity. However, the electrical impedance of small transducer elements is high and their efficiency is low and it has been difficult to manufacture arrays with adequate acoustic power. In this talk we will describe how these challenges can be solved with novel manufacturing methods and how we developed complete image-guided systems for both animal and clinical testing. We will also describe our experience with these systems for both brain and body treatments.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.002
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.002
Science and technology studies0.0000.001
Scholarly communication0.0020.002
Open science0.0010.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.294
Teacher spread0.280 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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