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Record W4367310173 · doi:10.3390/fractalfract7050361

In Vivo HIV Dynamics, Modeling the Interaction of HIV and Immune System via Non-Integer Derivatives

2023· article· en· W4367310173 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueFractal and Fractional · 2023
Typearticle
Languageen
FieldMedicine
TopicMathematical and Theoretical Epidemiology and Ecology Models
Canadian institutionsUniversity of Victoria
FundersTaif University
KeywordsProsperityImmune systemLife expectancyChaoticSystem dynamicsHuman immunodeficiency virus (HIV)Computer scienceControl theory (sociology)BiologyVirologyEconomicsImmunologyControl (management)MedicineEnvironmental healthEconomic growthArtificial intelligencePopulation

Abstract

fetched live from OpenAlex

The economic burden of HIV extends beyond the individual level and affects communities and countries. HIV can lead to decreased economic growth due to lost productivity and increased healthcare costs. In some countries, the HIV epidemic has led to a reduction in life expectancy, which can impact the overall quality of life and economic prosperity. Therefore, it is significant to investigate the intricate dynamics of this viral infection to know how the virus interacts with the immune system. In the current research, we will formulate the dynamics of HIV infection in the host body to conceptualize the interaction of T-cells and the immune system. The recommended model of HIV infection is presented with the help of fractional calculus for more precious outcomes. We introduce numerical methods to demonstrate how the input parameters affect the output of the system. The dynamical behavior and chaotic nature of the system are visualized with the variation of different input factors. The system’s tracking path has been numerically depicted and the impact of the viruses on T-cells has been demonstrated. In addition to this, the key factors of the system has been predicted through numerical findings. Our results predict that the strong non-linearity of the system is responsible for the chaos and oscillation, which are so closely related. The chaotic parameters of the system are highlighted and are recommended for the control of the chaos of the system.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.952
Threshold uncertainty score0.225

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.277
Teacher spread0.259 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it