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Record W4367595762 · doi:10.29007/2qhl

An Association Analysis of Breast Cancer with Carotenoids.

2023· article· en· W4367595762 on OpenAlexaff
Samuel Neumann, Mohamad El-Hajj

Bibliographic record

VenueEPiC series in computing · 2023
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCancer, Lipids, and Metabolism
Canadian institutionsMacEwan UniversityUniversity of Alberta
Fundersnot available
KeywordsExposomeBreast cancerCancerMedicineCarcinogenesisOncologyBioinformaticsEnvironmental healthBiologyInternal medicine

Abstract

fetched live from OpenAlex

The environment and the exposure individuals carry throughout their lifetime can gar- ner diverse effects on their health. This paper discusses the application of association analysis, to determine relationships between carcinogenesis and the human exposome. Human exposome data from the World Health Organization was analyzed to determine associations between human exposure and breast cancer. The discovered associations outline specific factors that may be associated with the prevention or causation of breast cancer. We discovered an association between biomarkers in specific biospecimens and breast cancer. Xanthophylls, measured in two different biospecimens, were determined to be associated with American breast cancer patients. The associations discovered may be of use in future cancer studies. This research is particularly interesting because of xanthophylls’ relationship to retinol, inhibiting oncogenesis. Providing support and data for such associations will encourage more research on the exposome’s effect on breast cancer and other conditions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.267
Teacher spread0.261 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2023
Admission routes1
Has abstractyes

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