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Record W4367680883 · doi:10.1101/2023.04.29.23289226

Development of the PSYCHS: Positive SYmptoms and Diagnostic Criteria for the CAARMS Harmonized with the SIPS

2023· preprint· en· W4367680883 on OpenAlexaff
Scott W. Woods, Sophie Parker, Melissa Kerr, Barbara C. Walsh, S. Andrea Wijtenburg, Nicholas Prunier, Ángela Núñez, Kate Buccilli, Catalina Mourgues, Kali Brummitt, Kyle S. Kinney, Carli Trankler, Julia Szacilo, Beau‐Luke Colton, Munaza Ali, Anastasia Haidar, Tashrif Billah, Kevin Huynh, Uzair Ahmed, Laura Adery, Cheryl M. Corcoran, Diana O. Perkins, Jason Schiffman, Jesús Pérez, Daniel Mamah, Lauren M. Ellman, Albert R. Powers, Michael J. Coleman, Alan Anticevic, Paolo Fusar‐Poli, John M. Kane, René S. Kahn, Patrick D. McGorry, Carrie E. Bearden, Martha E. Shenton, Barnaby Nelson, Monica E. Calkins, Larry D. Hendricks, Sylvain Bouix, Jean Addington, Thomas H. McGlashan, Alison R. Yung, Kelly Allott, Scott Clark, Tina Kapur, Suzie Lavoie, Kathryn E. Lewandowski, Daniel H. Mathalon, Ofer Pasternak, William S. Stone, John Torous, Laura M. Rowland, Ming Zhan, G. Paul Amminger, Celso Arango, Matthew R. Broome, Kristin S. Cadenhead, Eric Chen, Jimmy Choi, Kang Ik Kevin Cho, Philippe Conus, Barbara A. Cornblatt, Louise Birkedal Glenthøj, Leslie E. Horton, Joseph Kambeitz, Matcheri S. Keshavan, Nikolaos Koutsouleris, Kerstin Langbein, Covadonga M. Díaz‐Caneja, Vijay A. Mittal, Merete Nordentoft, P. Ramos, Godfrey D. Pearlson, Jai Shah, Stefan Smesny, Gregory P. Strauss, Jijun Wang, Patricia Marcy, Priya Matneja, Christina Phassouliotis, Susan Ray, Collum Snowball, Jessica Spark, Sophie Tod

Bibliographic record

VenuemedRxiv · 2023
Typepreprint
Languageen
FieldMedicine
TopicSchizophrenia research and treatment
Canadian institutionsMcGill UniversityDouglas CollegeUniversité du Québec à MontréalÉcole de Technologie SupérieureUniversity of Calgary
FundersNational Institute of Mental HealthNational Institutes of HealthFoundation for the National Institutes of Health
KeywordsPsychologyCognitive psychology

Abstract

fetched live from OpenAlex

Aim: To harmonize two ascertainment and severity rating instruments commonly used for the clinical high risk syndrome for psychosis (CHR-P): the Structured Interview for Psychosis-risk Syndromes (SIPS) and the Comprehensive Assessment of At-Risk Mental States (CAARMS). Methods: The initial workshop is described in the companion report from Addington et al. After the workshop, lead experts for each instrument continued harmonizing attenuated positive symptoms and criteria for psychosis and CHR-P through an intensive series of joint videoconferences. Results: Full harmonization was achieved for attenuated positive symptom ratings and psychosis criteria, and partial harmonization for CHR-P criteria. The semi-structured interview, named P ositive SY mptoms and Diagnostic Criteria for the C AARMS H armonized with the S IPS (PSYCHS), generates CHR-P criteria and severity scores for both CAARMS and SIPS. Conclusion: Using the PSYCHS for CHR-P ascertainment, conversion determination, and attenuated positive symptom severity rating will help in comparing findings across studies and in meta-analyses.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.033
metaresearch head score (Gemma)0.047
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.033
Threshold uncertainty score0.172

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0330.047
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.003
Bibliometrics0.0040.002
Science and technology studies0.0010.001
Scholarly communication0.0020.001
Open science0.0020.005
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0050.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.055
GPT teacher head0.335
Teacher spread0.280 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations21
Published2023
Admission routes1
Has abstractyes

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