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Proksee: in-depth characterization and visualization of bacterial genomes

2023· article· en· 1,720 citations· W4368358104 on OpenAlex· 10.1093/nar/gkad326

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Opus teacher head0.039
GPT teacher head0.337
Teacher spread
0.298 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

Proksee (https://proksee.ca) provides users with a powerful, easy-to-use, and feature-rich system for assembling, annotating, analysing, and visualizing bacterial genomes. Proksee accepts Illumina sequence reads as compressed FASTQ files or pre-assembled contigs in raw, FASTA, or GenBank format. Alternatively, users can supply a GenBank accession or a previously generated Proksee map in JSON format. Proksee then performs assembly (for raw sequence data), generates a graphical map, and provides an interface for customizing the map and launching further analysis jobs. Notable features of Proksee include unique and informative assembly metrics provided via a custom reference database of assemblies; a deeply integrated high-performance genome browser for viewing and comparing analysis results at individual base resolution (developed specifically for Proksee); an ever-growing list of embedded analysis tools whose results can be seamlessly added to the map or searched and explored in other formats; and the option to export graphical maps, analysis results, and log files for data sharing and research reproducibility. All these features are provided via a carefully designed multi-server cloud-based system that can easily scale to meet user demand and that ensures the web server is robust and responsive.

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The record

Venue
Nucleic Acids Research
Topic
Genomics and Phylogenetic Studies
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
University of ManitobaPublic Health Agency of CanadaUniversity of Alberta
Funders
Alliance de recherche numérique du CanadaGenome AlbertaGenome Canada
Keywords
JSONGenBankVisualizationComputer scienceGraphical user interfaceWeb serverReference genomeBiologyContigGenomeFile formatInformation retrievalData miningDatabaseThe InternetWorld Wide WebOperating systemGenetics
Has abstract in OpenAlex
yes